Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 5/20 | 0.45 |
| ▸ | NPBWR1 | P48145 | 10/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | RELA | Q04206 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | STAT1 | P42224 | 1/20 | 0.43 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.43 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.43 |
| ▸ | CHEK2 | O96017 | 3/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7398037 | 0.88 | GABRA1 (0.43) | NPBWR1NPC1MAPTHTTRAB9A | |
| SCHEMBL7394008 | 0.85 | NPBWR1 (0.58) | NPBWR1NPC1MAPTHTTRAB9A | |
| SCHEMBL7396372 | 0.83 | RAB9A (0.53) | NPBWR1NPC1MAPTHTTRAB9A | |
| SCHEMBL7396880 | 0.82 | NPBWR1 (0.51) | AMY1ANPBWR1NPC1MAPTRAB9A | |
| SCHEMBL7395955 | 0.81 | NPBWR1 (0.56) | AMY1ANPBWR1NPC1MAPTHTT | |
| SCHEMBL7393384 | 0.79 | NPBWR1 (0.51) | AMY1ANPBWR1NPC1MAPTHTT | |
| SCHEMBL7389163 | 0.79 | NPBWR1 (0.53) | AMY1ANPBWR1NPC1MAPTHTT | |
| SCHEMBL7389035 | 0.77 | AMY1A (0.53) | AMY1ANPBWR1NPC1MAPTHTT | |
| SCHEMBL7395960 | 0.74 | NPBWR1 (0.69) | AMY1ANPBWR1NPC1MAPTHTT | |
| SCHEMBL4497810 | 0.71 | NPBWR1 (0.65) | AMY1ANPBWR1NPC1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001066526-A1 | ESTER DERIVATIVES OF DIMETHYLPROPIONIC ACID AND PHARMACETUICAL COMPOSITIONS CONTAINING THEM | CERMOL S.A. (CH) | 2001-09-13 | — | — | WO | claimed |
| EP-1132381-A1 | Ester derivatives of dimethylpropionic acid and pharmaceutical compositions containing them | CERMOL S.A. (CH) | 2001-09-12 | — | — | EP | claimed |
| WO-2001066526-A1 | ESTER DERIVATIVES OF DIMETHYLPROPIONIC ACID AND PHARMACETUICAL COMPOSITIONS CONTAINING THEM | CERMOL S.A. (CH) | 2001-09-13 | — | — | WO | disclosed |
| EP-1132381-A1 | Ester derivatives of dimethylpropionic acid and pharmaceutical compositions containing them | CERMOL S.A. (CH) | 2001-09-12 | — | — | EP | disclosed |