Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Ether. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ether SCHEMBL6514000 | 0.97 | ALDH1A1 (0.41) | ALDH1A1TSHRCA5ACA5BTP53 | |
| Ether SCHEMBL1016951 | 0.94 | ALDH1A1 (0.46) | ALDH1A1TSHRCA5ACA5BTP53 | |
| Ether SCHEMBL27570944 | 0.94 | CA5A (0.43) | ALDH1A1TSHRCA5ACA5BTP53 | |
| Ether SCHEMBL38466 | 0.94 | CA5A (0.43) | ALDH1A1TSHRCA5ACA5BTP53 | |
| Ether SCHEMBL2403925 | 0.92 | ALDH1A1 (0.43) | ALDH1A1TSHRCA5ACA5BTP53 | |
| Ether SCHEMBL10401617 | 0.91 | ALDH1A1 (0.48) | ALDH1A1TSHRCA5ACA5BTP53 | |
| Ether SCHEMBL828632 | 0.90 | CA5A (0.40) | ALDH1A1TSHRCA5ACA5BTP53 | |
| Ether SCHEMBL19813170 | 0.90 | CA5A (0.40) | ALDH1A1TSHRCA5ACA5BTP53 | |
| Ether SCHEMBL1095738 | 0.90 | CA5A (0.40) | ALDH1A1TSHRCA5ACA5BTP53 | |
| Ether SCHEMBL9221305 | 0.90 | CA5A (0.40) | ALDH1A1TSHRCA5ACA5BTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 166 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112961739-A | Efficient foam cleaning disinfectant special for farm | 湖南广安动物保健品有限公司 | 2021-06-15 | — | — | CN | claimed |
| CN-109811148-B | Method for recovering soluble sulfate by piling and washing manganic acid leaching residues | 贵州大学 | 2021-05-14 | — | — | CN | claimed |
| CN-110272174-A | A kind of alkalinity release agent and the application in oil sludge processing | 陕西欧菲德环保科技有限公司 | 2019-09-24 | — | — | CN | claimed |
| CN-109456855-A | A kind of environment protection clean type greasy dirt detergent and preparation method thereof | 夏勇 | 2019-03-12 | — | — | CN | claimed |
| CN-106634921-B | The continuous online production of viscous oil emulsion particle diverting agent and injection integral method | 中国石油大学(华东) | 2018-07-06 | — | — | CN | claimed |
| CN-108085149-A | A kind of high-efficiency disinfection liquid detergent | 石羽 | 2018-05-29 | — | — | CN | claimed |
| CN-107794495-A | A kind of complex alloy permeation agent | 安徽瑞合铁路紧固件科技有限公司 | 2018-03-13 | — | — | CN | claimed |
| CN-107057880-A | Graphene antibiosis complex liquid and preparation method thereof | 南通强生石墨烯科技有限公司 | 2017-08-18 | — | — | CN | claimed |
| CN-106497691-A | Two-in-one high foam washing car wax and its preparation, the method for using | 江阴樱花梦家庭用品有限公司 | 2017-03-15 | — | — | CN | claimed |
| CN-104023530-A | Short-chain alkylsulfonates in pesticide formulations and application | AKZO NOBEL CHEMICALS INT BV | 2014-09-03 | — | — | CN | claimed |
| CN-103789101-A | Acid harsh detergent | HE LIPING | 2014-05-14 | — | — | CN | claimed |
| CN-103668275-A | Preparation method of degreasant applicable to spray degreasing | TIANJIN DAGANG GALVANIZED FACTORY | 2014-03-26 | — | — | CN | claimed |
| CN-103668276-A | Preparation method of efficient degreasing agent | TIANJIN DAGANG GALVANIZED FACTORY | 2014-03-26 | — | — | CN | claimed |
| CN-103484265-A | Green antibacterial efficient cleanser essence and preparation method thereof | CHEN LIJING | 2014-01-01 | — | — | CN | claimed |
| CN-103131405-A | High-temperature sea water-base fracturing liquid suitable for formation temperature of 160 DEG C and preparation method thereof | CHINA NAT OFFSHORE OIL CORP | 2013-06-05 | — | — | CN | claimed |
| CN-102965962-A | Method for obtaining one-way moisture conduction fabric by use of foam finishing | HUNAN INST ENGINEERING | 2013-03-13 | — | — | CN | claimed |
| EP-0353976-B1 | Detergents | CUSSONS INT LTD (GB) | 1993-12-01 | — | — | EP | claimed |
| EP-0404865-A1 | DETERGENTS | PATERSON, ZOCHONIS (U.K.) LIMITED (GB) | 1991-01-02 | — | — | EP | claimed |
| WO-1990001536-A1 | DETERGENTS | CUSSONS (INTERNATIONAL) LIMITED (GB) | 1990-02-22 | — | — | WO | claimed |
| EP-0353976-A1 | Detergents | Cussons (International) Limited (GB) | 1990-02-07 | — | — | EP | claimed |