Ether

Ether

SCHEMBL828632

CCOCC.O=S(=O)(O)O.[NaH]

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Ether. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CA5A P35218 1/20 0.40
CA5B Q9Y2D0 1/20 0.40
ALDH1A1 P00352 4/20 0.38
TP53 P04637 1/20 0.37
CA2 P00918 2/20 0.36
CA1 P00915 1/20 0.36
TSHR P16473 1/20 0.36
LMNA P02545 1/20 0.32
HSD17B10 Q99714 1/20 0.32
THRB P10828 1/20 0.31
ALOX15 P16050 1/20 0.30
MGAM O43451 1/20 0.30
GAA P10253 1/20 0.30
SI P14410 1/20 0.30
MGAM2 Q2M2H8 1/20 0.30
SOAT1 P35610 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ether SCHEMBL38466 0.97 CA5A (0.43) CA5ACA5BALDH1A1TP53CA2
Ether SCHEMBL27570944 0.97 CA5A (0.43) CA5ACA5BALDH1A1TP53CA2
Ether SCHEMBL7991028 0.93 CA5A (0.40) CA5ACA5BALDH1A1TP53CA2
Ether SCHEMBL4926932 0.93 CA5A (0.40) CA5ACA5BALDH1A1TP53CA2
Ether SCHEMBL1095738 0.93 CA5A (0.40) CA5ACA5BALDH1A1TP53CA2
Ether SCHEMBL9221305 0.93 CA5A (0.40) CA5ACA5BALDH1A1TP53CA2
Ether SCHEMBL19813170 0.93 CA5A (0.40) CA5ACA5BALDH1A1TP53CA2
Ether SCHEMBL28102344 0.93 CA5A (0.40) CA5ACA5BALDH1A1TP53CA2
Ether SCHEMBL27956426 0.90 ALDH1A1 (0.36) ALDH1A1TP53CA2CA1TSHR
Ether SCHEMBL739042 0.90 ALDH1A1 (0.43) CA5ACA5BALDH1A1TP53CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4032 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117624485-A Microgel acrylic emulsion and preparation method and application thereof 广东恒和永盛集团有限公司 2024-03-01 CN claimed
CN-117625161-A Oil-in-water emulsion type wax remover and preparation method and application thereof 中国石油天然气股份有限公司 2024-03-01 CN claimed
CN-112534021-B Resin composition for vibration damping material 株式会社日本触媒 2023-12-15 CN claimed
WO-2023115690-A1 WATER-RESISTANT AND HIGH-STRENGTH GYPSUM PLASTERBOARD AND PREPARATION METHOD THEREFOR 中建材创新科技研究院有限公司 2023-06-29 WO claimed
CN-115927541-B Stable anti-freezing virus preservation solution 山东博科生物产业有限公司 2023-06-27 CN claimed
CN-115927541-A Stable anti-freezing virus preservation solution 山东博科生物产业有限公司 2023-04-07 CN claimed
CN-115720902-A Traditional Chinese medicine spray for treating ectoparasites of pets 郑州赛科药业科技有限公司 2023-03-03 CN claimed
CN-115491179-A Dust suppressant for field 中国铁路北京局集团有限公司北京科学技术研究所 2022-12-20 CN claimed
CN-113560261-A Oil and rust removing treatment method for transformer surface 句容市江电电器机械有限公司 2021-10-29 CN claimed
CN-113512405-A Composite dust suppressant and preparation method and application thereof 中国矿业大学(北京) 2021-10-19 CN claimed
CN-1056525-A Oil is suffered from son, the neutral efficient detergent of Chinese honey locust WENJIANG INST OF BIOCHEMICAL A (CN) 1991-11-27 CN claimed
CN-1055961-A EFFICIENT DETERGENT FOR DEGREASING AND RUST REMOVAL AT ORDINARY TEMP LIAO ZHONGWEI (CN) 1991-11-06 CN claimed
CN-1055948-A The production method of emulgent for fuel oil and emulsified fuel ZHANG ZEBIN (CN) 1991-11-06 CN claimed
CN-1055960-A EFFICIENT PAINT FOR DEGREASING AND RUST REMOVAL AT ORDINARY TEMP LIAO ZHONGWEI (CN) 1991-11-06 CN claimed
CN-1052986-A First, hepatitis type B virus, venereal disease disinfectant LI JIUCHUN (CN) 1991-07-17 CN claimed
CN-1052625-A Welding stopping agent for area welding PETROCHEMICAL SCIENCE PRESEARC (CN) 1991-07-03 CN claimed
CN-1045332-A Disinfectant for animals and production technology LI JIUCHUN (CN) 1990-09-19 CN claimed
CN-1008602-B The electricity consumption filter method changes the performance of dispersion resin GOODRICH CO B F (US) 1990-07-04 CN claimed
CN-86108087-A The electricity consumption filter method changes the performance of dispersion resin 1987-08-05 CN claimed
CN-85103236-A LIQUID DETERGENT COMPOSITIONS 1986-07-02 CN claimed