Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.61 |
| ▸ | GABRP | O00591 | 4/20 | 0.61 |
| ▸ | GABRD | O14764 | 4/20 | 0.61 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.61 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.61 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.61 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.61 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.61 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.61 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.61 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.61 |
| ▸ | GABRA4 | P48169 | 4/20 | 0.61 |
| ▸ | GABRE | P78334 | 4/20 | 0.61 |
| ▸ | GABRA6 | Q16445 | 4/20 | 0.61 |
| ▸ | GABRG1 | Q8N1C3 | 4/20 | 0.61 |
| ▸ | GABRG3 | Q99928 | 4/20 | 0.61 |
| ▸ | GABRQ | Q9UN88 | 4/20 | 0.61 |
| ▸ | UGT1A1 | P22309 | 3/20 | 0.61 |
| ▸ | PKM | P14618 | 3/20 | 0.61 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL971282 | 0.90 | ABCB1 (0.61) | KMT2AGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL737402 | 0.87 | MAPT (0.63) | KMT2AGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL6412437 | 0.80 | UGT1A1 (0.65) | KMT2AUGT1A1CYP1A1CYP1B1FTO | |
| SCHEMBL737399 | 0.78 | ACHE (0.53) | ABCB1MAOAMAOBBCHEACHE | |
| Pisonin E SCHEMBL30879929 | 0.77 | PTGS1 (0.56) | UGT1A1UGT1A8MAPTKDM4ECYP3A4 | |
| Scutellarein SCHEMBL29692708 | 0.76 | KMT2A (1.00) | KMT2AGABRPGABRDGABRA1GABRB1 | |
| Scutellarein SCHEMBL142093 | 0.76 | KMT2A (1.00) | KMT2AGABRPGABRDGABRA1GABRB1 | |
| Scutellarein SCHEMBL29004586 | 0.76 | KMT2A (1.00) | KMT2AGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL24088771 | 0.75 | CBS (0.82) | KMT2AGABRPGABRDGABRA1GABRB1 | |
| Scutellarein SCHEMBL15090395 | 0.75 | KMT2A (0.97) | KMT2AGABRPGABRDGABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138165-B2 | Chromones and chromone derivatives and uses thereof | JENKEN BIOSCIENCES, INC. (US) | 2012-03-20 | — | — | US | disclosed |
| EP-1556031-A4 | CHROMONES AND CHROMONE DERIVATIVES AND USES THEREOF | JENKEN BIOSCIENCES INC (US) | 2009-03-25 | — | — | EP | disclosed |
| US-20060142211-A1 | Chromones and chromone derivatives and uses thereof | TAIWANJ PHARMACEUTICALS CO., LTD. (TW) | 2006-06-29 | — | — | US | disclosed |
| EP-1556031-A2 | CHROMONES AND CHROMONE DERIVATIVES AND USES THEREOF | Jenken Bioscience, Inc. (US) | 2005-07-27 | — | — | EP | disclosed |
| WO-2004037193-A2 | CHROMONES AND CHROMONE DERIVATIVES AND USES THEREOF | JENKEN BIOSCIENCES, INC. (US) | 2004-05-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060142211-A1 | Chromones and chromone derivatives and uses thereof | PROC, HMGB1, PYCARD | KMT2A 4070/4885GABRP 4406/4885GABRD 4855/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.