Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGT1A1 | P22309 | 1/20 | 0.65 |
| ▸ | UGT1A8 | Q9HAW9 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 9/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.58 |
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.58 |
| ▸ | ABCB1 | P08183 | 6/20 | 0.58 |
| ▸ | TP53 | P04637 | 5/20 | 0.58 |
| ▸ | FTO | Q9C0B1 | 5/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | HPGD | P15428 | 4/20 | 0.58 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.58 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29118562 | 0.82 | FBP1 (0.65) | UGT1A1UGT1A8MEN1KMT2ACYP3A4 | |
| SCHEMBL739211 | 0.80 | KMT2A (0.61) | UGT1A1UGT1A8MEN1KMT2ACYP3A4 | |
| SCHEMBL12073700 | 0.79 | UGT1A1 (1.00) | UGT1A1UGT1A8MEN1KMT2ACYP3A4 | |
| Tryptanthrin SCHEMBL6918387 | 0.78 | TDO2 (0.48) | UGT1A1UGT1A8MEN1KMT2ACYP3A4 | |
| SCHEMBL26679504 | 0.78 | UGT1A1 (0.56) | UGT1A1UGT1A8MEN1KMT2ACYP3A4 | |
| SCHEMBL30637545 | 0.78 | UGT1A1 (0.56) | UGT1A1UGT1A8MEN1KMT2ACYP3A4 | |
| 6-Hydroxykaempferol SCHEMBL674949 | 0.76 | AMY1A (0.76) | UGT1A1MEN1KMT2ACYP3A4MAPT | |
| 6-Hydroxykaempferol SCHEMBL29725747 | 0.76 | AMY1A (0.76) | UGT1A1MEN1KMT2ACYP3A4MAPT | |
| SCHEMBL29569956 | 0.75 | MEN1 (0.71) | MEN1KMT2ACYP3A4MAPTKDM4E | |
| SCHEMBL17938762 | 0.75 | XDH (0.69) | MEN1KMT2AMAPTKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0987027-B1 | Ethyl acetate extract from Indigo plant | HAYASHIBARA BIOCHEM LAB (JP) | 2004-08-11 | — | — | EP | claimed |
| US-6524625-B2 | Soaking raw indigo plant in organic solvent containing ethyl acetate-soluble ingredient (kaempferol); extract useful as antiseptic, viricide, antitumor agent, apoptosis-/cytokine production- controlling agent, enzyme inhibitors | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUTO (JP) | 2003-02-25 | — | — | US | claimed |
| US-20020068094-A1 | PHYSIOLOGICALLY ACTIVE EXRACT | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2002-06-06 | — | — | US | claimed |
| EP-0987027-A1 | Physiologically active extract | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2000-03-22 | — | — | EP | claimed |
| CN-117180260-A | Deoxyflavonoid-based T lymphocyte activity inhibition composition | 杭州卢特康生物科技有限公司 | 2023-12-08 | — | — | CN | disclosed |
| WO-2005076757-A2 | HAIR AND EYEBROW, EYELASHES GROWTH STIMULATER | LG HOUSEHOLD & HEALTH CARE LTD. (KR) | 2005-08-25 | — | — | WO | disclosed |
| EP-0987027-B1 | Ethyl acetate extract from Indigo plant | HAYASHIBARA BIOCHEM LAB (JP) | 2004-08-11 | — | — | EP | disclosed |
| US-6524625-B2 | Soaking raw indigo plant in organic solvent containing ethyl acetate-soluble ingredient (kaempferol); extract useful as antiseptic, viricide, antitumor agent, apoptosis-/cytokine production- controlling agent, enzyme inhibitors | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUTO (JP) | 2003-02-25 | — | — | US | disclosed |
| US-6524625-B2 | Soaking raw indigo plant in organic solvent containing ethyl acetate-soluble ingredient (kaempferol); extract useful as antiseptic, viricide, antitumor agent, apoptosis-/cytokine production- controlling agent, enzyme inhibitors | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUTO (JP) | 2003-02-25 | — | — | US | disclosed |
| US-20020068094-A1 | PHYSIOLOGICALLY ACTIVE EXRACT | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2002-06-06 | — | — | US | disclosed |
| US-20020068094-A1 | PHYSIOLOGICALLY ACTIVE EXRACT | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2002-06-06 | — | — | US | disclosed |
| EP-0987027-A1 | Physiologically active extract | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2000-03-22 | — | — | EP | disclosed |
| EP-0987027-A1 | Physiologically active extract | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2000-03-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020068094-A1 | PHYSIOLOGICALLY ACTIVE EXRACT | SI, TYR, COMT | UGT1A1 382/4885UGT1A8 293/4885MEN1 2577/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.