Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 9/20 | 0.46 |
| ▸ | PDE5A | O76074 | 3/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.39 |
| ▸ | MAP2 | P11137 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7978070 | 0.87 | AMY1A (0.47) | AMY1ARAB9ANPC1POLBKLF5 | |
| SCHEMBL7392857 | 0.86 | RAB9A (0.49) | AMY1ARAB9ANPC1POLBKLF5 | |
| SCHEMBL7399325 | 0.86 | RAB9A (0.47) | AMY1ARAB9ANPC1POLBKLF5 | |
| SCHEMBL7396331 | 0.86 | KDM4E (0.53) | AMY1APDE5ARAB9ANPC1KDM4E | |
| SCHEMBL7387113 | 0.84 | AMY1A (0.42) | AMY1ARAB9ANPC1POLBKLF5 | |
| SCHEMBL7389024 | 0.84 | AMY1A (0.54) | AMY1APDE5AELANERAB9ANPC1 | |
| SCHEMBL7396880 | 0.83 | NPBWR1 (0.51) | AMY1ARAB9ANPC1 | |
| SCHEMBL7396624 | 0.82 | F2 (0.42) | AMY1ARAB9ANPC1POLBALDH1A1 | |
| SCHEMBL7992209 | 0.80 | AMY1A (0.43) | AMY1ARAB9ANPC1POLBKLF5 | |
| SCHEMBL23758274 | 0.80 | AMY1A (0.64) | AMY1APDE5AELANEMAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001066526-A1 | ESTER DERIVATIVES OF DIMETHYLPROPIONIC ACID AND PHARMACETUICAL COMPOSITIONS CONTAINING THEM | CERMOL S.A. (CH) | 2001-09-13 | — | — | WO | claimed |
| EP-1132381-A1 | Ester derivatives of dimethylpropionic acid and pharmaceutical compositions containing them | CERMOL S.A. (CH) | 2001-09-12 | — | — | EP | claimed |
| WO-2001066526-A1 | ESTER DERIVATIVES OF DIMETHYLPROPIONIC ACID AND PHARMACETUICAL COMPOSITIONS CONTAINING THEM | CERMOL S.A. (CH) | 2001-09-13 | — | — | WO | disclosed |
| EP-1132381-A1 | Ester derivatives of dimethylpropionic acid and pharmaceutical compositions containing them | CERMOL S.A. (CH) | 2001-09-12 | — | — | EP | disclosed |