Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | AMY1A | P0DUB6 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7392857 | 0.91 | RAB9A (0.49) | RAB9ANPC1POLBKLF5TDP1 | |
| SCHEMBL7392370 | 0.86 | AMY1A (0.46) | RAB9ANPC1POLBKLF5TDP1 | |
| SCHEMBL7396331 | 0.86 | KDM4E (0.53) | RAB9ANPC1AMY1AKDM4EALDH1A1 | |
| SCHEMBL7398763 | 0.81 | AMY1A (0.50) | RAB9ANPC1AMY1AKDM4EALDH1A1 | |
| SCHEMBL7992209 | 0.80 | AMY1A (0.43) | RAB9ANPC1POLBKLF5TDP1 | |
| SCHEMBL1483091 | 0.80 | AMY1A (0.65) | RAB9ANPC1POLBKLF5TDP1 | |
| SCHEMBL7396624 | 0.80 | F2 (0.42) | RAB9ANPC1POLBAMY1AALDH1A1 | |
| SCHEMBL7397419 | 0.80 | KDM4E (0.52) | RAB9ANPC1POLBAMY1AKDM4E | |
| SCHEMBL7387113 | 0.78 | AMY1A (0.42) | RAB9ANPC1POLBKLF5TDP1 | |
| SCHEMBL7978070 | 0.77 | AMY1A (0.47) | RAB9ANPC1POLBKLF5TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001066526-A1 | ESTER DERIVATIVES OF DIMETHYLPROPIONIC ACID AND PHARMACETUICAL COMPOSITIONS CONTAINING THEM | CERMOL S.A. (CH) | 2001-09-13 | — | — | WO | claimed |
| EP-1132381-A1 | Ester derivatives of dimethylpropionic acid and pharmaceutical compositions containing them | CERMOL S.A. (CH) | 2001-09-12 | — | — | EP | claimed |
| EP-1132381-A1 | Ester derivatives of dimethylpropionic acid and pharmaceutical compositions containing them | CERMOL S.A. (CH) | 2001-09-12 | — | — | EP | disclosed |