Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 5/20 | 0.38 |
| ▸ | CCKBR | P32239 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 4/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.37 |
| ▸ | CTSS | P25774 | 3/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 3/20 | 0.36 |
| ▸ | CTSB | P07858 | 2/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7393379 | 0.94 | CASP1 (0.38) | SIRT2CASP1SIRT1CTSSCTSL | |
| Hydrochloric Acid SCHEMBL9003069 | 0.94 | CASP1 (0.37) | SIRT2CASP1SIRT1CTSSCTSL | |
| SCHEMBL7395541 | 0.89 | CTSK (0.40) | CASP1CTSSCTSLCTSKCTSB | |
| SCHEMBL7392968 | 0.87 | ITGB3 (0.39) | SIRT2CCKBRCASP1CTSSCTSL | |
| SCHEMBL9002874 | 0.85 | F2 (0.40) | SIRT2CCKBRCASP1SIRT1CTSS | |
| SCHEMBL7395266 | 0.85 | CASP1 (0.40) | CASP1CTSSCTSLCTSKCTSB | |
| Hydrochloric Acid SCHEMBL9002904 | 0.84 | CASP1 (0.39) | CASP1CTSSCTSLCTSKCTSB | |
| SCHEMBL9002766 | 0.82 | BCHE (0.40) | SIRT2CCKBRCASP1SIRT1CTSS | |
| Hydrochloric Acid SCHEMBL9002721 | 0.81 | BCHE (0.40) | SIRT2CCKBRCASP1SIRT1CTSS | |
| SCHEMBL7393462 | 0.81 | L3MBTL1 (0.38) | SIRT2CASP1CTSSCTSLITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5559232-A | ANTICOAGULANTS | HOFFMANN-LA ROCHE INC. (US) | 1996-09-24 | — | — | US | disclosed |
| EP-0641779-A1 | Novel 1-amidinopiperdines and 4-amidinomorpholines as aggregation inhibitions | F. HOFFMANN-LA ROCHE AG (CH) | 1995-03-08 | — | — | EP | disclosed |