Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 2/20 | 0.56 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.54 |
| ▸ | MMP2 | P08253 | 3/20 | 0.53 |
| ▸ | MMP9 | P14780 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.52 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.52 |
| ▸ | TGM2 | P21980 | 1/20 | 0.50 |
| ▸ | ACE | P12821 | 2/20 | 0.49 |
| ▸ | DPP4 | P27487 | 1/20 | 0.49 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.49 |
| ▸ | MMP1 | P03956 | 1/20 | 0.49 |
| ▸ | MMP3 | P08254 | 1/20 | 0.49 |
| ▸ | MMP7 | P09237 | 1/20 | 0.49 |
| ▸ | MMP13 | P45452 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30689097 | 0.82 | FOLH1 (0.64) | FOLH1MMP2MMP9HTTDPP8 | |
| SCHEMBL7938432 | 0.82 | ABCB1 (0.61) | FOLH1ABCB1HTT | |
| SCHEMBL7390273 | 0.82 | FOLH1 (0.58) | FOLH1MMP2MMP9HTTDPP8 | |
| SCHEMBL5858019 | 0.81 | HTT (0.62) | FOLH1HTTDPP8DPP7TGM2 | |
| SCHEMBL464671 | 0.80 | FOLH1 (0.64) | FOLH1MMP2MMP9HTTDPP8 | |
| SCHEMBL7323375 | 0.78 | FOLH1 (0.66) | FOLH1MMP2MMP9ACEMMP1 | |
| SCHEMBL17244715 | 0.78 | SIRT5 (0.62) | FOLH1HTT | |
| SCHEMBL18789039 | 0.78 | FOLH1 (0.62) | FOLH1MMP2MMP9HTTDPP8 | |
| SCHEMBL8393267 | 0.78 | HTT (0.65) | FOLH1HTTDPP8DPP7TGM2 | |
| SCHEMBL10772400 | 0.78 | FOLH1 (0.68) | FOLH1MMP2MMP9ACEMMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263716-A2 | AMINO ACID DERIVATIVES AS HIV ASPARTYL PROTEASE INHIBITORS | Pharmacor Inc. (CA) | 2002-12-11 | — | — | EP | disclosed |
| WO-2001068593-A2 | AMINO ACID DERIVATIVES AS HIV ASPARTYL PROTEASE INHIBITORS | PHARMACOR INC. (CA) | 2001-09-20 | — | — | WO | disclosed |