Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28981555 | 0.92 | ALOX15 (0.44) | ALDH1A1TSHRALOX15HRH3 | |
| SCHEMBL375328 | 0.83 | SIGMAR1 (0.37) | ALDH1A1ALOX15HRH3 | |
| SCHEMBL7384824 | 0.81 | — | — | |
| SCHEMBL7389963 | 0.81 | — | — | |
| SCHEMBL8471267 | 0.79 | HRH3 (0.56) | ALDH1A1TSHRALOX15HRH3 | |
| SCHEMBL16312397 | 0.77 | HRH3 (0.61) | ALDH1A1TSHRALOX15HRH3 | |
| SCHEMBL1782004 | 0.77 | PAOX (0.47) | ALDH1A1TSHRALOX15 | |
| SCHEMBL9766420 | 0.77 | GNAI3 (0.55) | ALDH1A1 | |
| SCHEMBL8805965 | 0.77 | GNAI3 (0.55) | ALDH1A1 | |
| SCHEMBL4629578 | 0.77 | GNAI3 (0.55) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5864039-A | THERAPEUTIC TREATMENT OF VARIOUS GASTROINTESTINAL DISEASES, CENTRAL NERVOUS DISORDERS, CARDIOVASCULAR DISORDERS, URINARY DISEASES, UROGENITAL DISORDERS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1999-01-26 | — | — | US | disclosed |
| EP-0873990-A1 | BENZOIC ACID COMPOUNDS AND MEDICINAL USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-10-28 | — | — | EP | disclosed |