Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LAP3 | P28838 | 3/20 | 0.46 |
| ▸ | ANPEP | P15144 | 1/20 | 0.46 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.46 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.46 |
| ▸ | CCR1 | P32246 | 9/20 | 0.45 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.45 |
| ▸ | REN | P00797 | 2/20 | 0.45 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4070249 | 0.79 | SLC1A3 (0.49) | LAP3ANPEPRNPEPDNPEPCSNK1E | |
| SCHEMBL4066989 | 0.78 | REN (0.62) | LAP3CCR1REN | |
| SCHEMBL4068036 | 0.78 | REN (0.62) | LAP3CCR1REN | |
| SCHEMBL7436311 | 0.78 | SLC1A3 (0.68) | LAP3ANPEPRNPEPDNPEPSLC15A1 | |
| SCHEMBL7436306 | 0.78 | SLC1A3 (0.68) | LAP3ANPEPRNPEPDNPEPSLC15A1 | |
| SCHEMBL10591944 | 0.78 | PSEN1 (0.58) | CCR1REN | |
| SCHEMBL7357869 | 0.78 | PSEN1 (0.58) | CCR1REN | |
| SCHEMBL4060434 | 0.78 | MMP1 (0.41) | LAP3ANPEPRNPEPDNPEPCCR1 | |
| SCHEMBL4062972 | 0.77 | SLC1A3 (0.53) | LAP3ANPEPRNPEPDNPEPCCR1 | |
| SCHEMBL10444583 | 0.76 | LAP3 (0.44) | LAP3ANPEPRNPEPDNPEPCSNK1E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415981-A4 | RETROVIRAL PROTEASE INHIBITORS | — | 1991-10-09 | — | — | EP | disclosed |
| EP-0415981-A1 | RETROVIRAL PROTEASE INHIBITORS | ABBOTT LABORATORIES (US) | 1991-03-13 | — | — | EP | disclosed |
| EP-0342541-A2 | Retroviral protease inhibitors | ABBOTT LABORATORIES (US) | 1989-11-23 | — | — | EP | disclosed |
| WO-1989010752-A1 | RETROVIRAL PROTEASE INHIBITORS | ABBOTT LABORATORIES (US) | 1989-11-16 | — | — | WO | disclosed |