Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 3/20 | 0.38 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 5/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 5/20 | 0.36 |
| ▸ | USP7 | Q93009 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | KIT | P10721 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7396015 | 0.87 | FABP4 (0.37) | FABP4FABP5USP7HTR3AKCNH2 | |
| SCHEMBL9363873 | 0.87 | FABP4 (0.37) | FABP4FABP5USP7HTR3AKCNH2 | |
| SCHEMBL7395468 | 0.83 | FABP4 (0.36) | FABP4FABP5USP7HTR3ACA1 | |
| SCHEMBL7395839 | 0.80 | NPC1 (0.37) | FABP4FABP5HCRTR1HCRTR2HTR3A | |
| SCHEMBL9359539 | 0.78 | ALDH1A1 (0.39) | FABP4FABP5NPSR1CA1CA2 | |
| SCHEMBL9359531 | 0.78 | ALDH1A1 (0.39) | FABP4FABP5NPSR1CA1CA2 | |
| SCHEMBL8909978 | 0.78 | FABP4 (0.39) | FABP4FABP5USP7LMNAHTR3A | |
| SCHEMBL9821920 | 0.75 | NPC1 (0.47) | HTTLMNANPSR1HTR3A | |
| SCHEMBL7401003 | 0.75 | NPC1 (0.47) | HTTLMNANPSR1HTR3A | |
| SCHEMBL9359521 | 0.74 | HTR3A (0.44) | FABP4FABP5LMNAHTR3AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0491770-A1 | SUBSTITUTED UREA COMPOUNDS AND THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1992-07-01 | — | — | EP | disclosed |
| WO-1991003475-A1 | SUBSTITUTED UREA COMPOUNDS AND THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1991-03-21 | — | — | WO | disclosed |