Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 13/20 | 0.54 |
| ▸ | ITGA2B | P08514 | 13/20 | 0.54 |
| ▸ | GBA1 | P04062 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.40 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.40 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.40 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7399183 | 0.73 | ITGB3 (0.56) | ITGB3ITGA2B | |
| SCHEMBL3199145 | 0.73 | LMNA (0.66) | KMT2AHPGD | |
| SCHEMBL1633286 | 0.72 | GBA1 (0.60) | ITGB3ITGA2BGBA1 | |
| SCHEMBL4971265 | 0.71 | NPC1 (0.58) | ITGB3ITGA2BGBA1ALDH1A1HPGD | |
| SCHEMBL16787792 | 0.71 | GBA1 (0.54) | ITGB3ITGA2BGBA1 | |
| SCHEMBL3199590 | 0.70 | MTNR1A (0.62) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL16790144 | 0.70 | GBA1 (0.50) | GBA1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7402093 | 0.70 | ITGB3 (0.82) | ITGB3ITGA2BKMT2ASMN1; SMN2ITGA2 | |
| SCHEMBL25788605 | 0.69 | GBA1 (0.46) | ITGB3ITGA2BGBA1 | |
| SCHEMBL7396150 | 0.69 | ITGB3 (0.72) | ITGB3ITGA2BITGA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0673247-A4 | FIBRINOGEN RECEPTOR ANTAGONISTS. | MERCK & CO INC (US) | 1996-05-01 | — | — | EP | claimed |
| EP-0673247-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO. INC. (US) | 1995-09-27 | — | — | EP | claimed |
| WO-1994012181-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1994-06-09 | — | — | WO | claimed |
| US-5648368-A | ANTICOAGULANTS | MERCK & CO., INC. (US) | 1997-07-15 | — | — | US | disclosed |
| EP-0673247-A4 | FIBRINOGEN RECEPTOR ANTAGONISTS. | MERCK & CO INC (US) | 1996-05-01 | — | — | EP | disclosed |
| EP-0673247-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO. INC. (US) | 1995-09-27 | — | — | EP | disclosed |
| WO-1994012181-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1994-06-09 | — | — | WO | disclosed |