Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 13/20 | 0.38 |
| ▸ | FNTB | P49356 | 13/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | F3 | P13726 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7403823 | 0.93 | MTNR1A (0.39) | MTNR1AMTNR1BMCL1ACMSD | |
| SCHEMBL7392200 | 0.86 | MTNR1A (0.47) | MTNR1AMTNR1BHTR6ALOX5 | |
| SCHEMBL7401683 | 0.85 | HDAC6 (0.40) | MTNR1AMTNR1B | |
| SCHEMBL7398662 | 0.84 | MTNR1A (0.37) | MTNR1AMTNR1BMCL1ACMSD | |
| SCHEMBL7396434 | 0.82 | MTNR1A (0.36) | MTNR1AMTNR1BMCL1ACMSD | |
| SCHEMBL7399608 | 0.80 | MTNR1A (0.37) | MTNR1AMTNR1BHTR6TLR8TLR7 | |
| SCHEMBL7400412 | 0.78 | MTNR1A (0.36) | MTNR1AMTNR1BHTR6MCL1ACMSD | |
| SCHEMBL7315194 | 0.72 | HTR6 (0.36) | FNTAFNTBHTR6MCL1ACMSD | |
| Hydrochloric Acid SCHEMBL7399520 | 0.68 | F2 (0.39) | MTNR1AMTNR1BHTR6MCL1ACMSD | |
| Hydrochloric Acid SCHEMBL7400195 | 0.68 | PPARG (0.39) | MTNR1AMTNR1BMCL1ACMSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034146-A1 | NOVEL ANTI-INFECTIVES | SMITHKLINE BEECHAM CORPORATION (US) | 2001-05-17 | — | — | WO | claimed |
| WO-2001034146-A1 | NOVEL ANTI-INFECTIVES | SMITHKLINE BEECHAM CORPORATION (US) | 2001-05-17 | — | — | WO | disclosed |