Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.36 |
| ▸ | CCNK | O75909 | 1/20 | 0.35 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | WNT1 | P04628 | 3/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.34 |
| ▸ | GSK3B | P49841 | 2/20 | 0.34 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7400412 | 0.82 | MTNR1A (0.36) | MTNR1AMTNR1BHTR6TLR8TLR7 | |
| SCHEMBL7396398 | 0.80 | FNTA (0.38) | MTNR1AMTNR1BHTR6TLR8TLR7 | |
| SCHEMBL7403823 | 0.78 | MTNR1A (0.39) | MTNR1AMTNR1BGSK3BADK | |
| SCHEMBL7396434 | 0.75 | MTNR1A (0.36) | MTNR1AMTNR1BKDM4EHSD17B10 | |
| SCHEMBL7398662 | 0.75 | MTNR1A (0.37) | MTNR1AMTNR1BKDM4EHSD17B10GSK3B | |
| SCHEMBL7392200 | 0.73 | MTNR1A (0.47) | MTNR1AMTNR1BHTR6KDM4EHSD17B10 | |
| SCHEMBL7314014 | 0.73 | HTR6 (0.35) | HTR6GSK3BGSK3AHTR2CCHEK1 | |
| SCHEMBL7401683 | 0.73 | HDAC6 (0.40) | MTNR1AMTNR1BHTR2C | |
| Hydrochloric Acid SCHEMBL7403768 | 0.68 | CA12 (0.42) | MTNR1AMTNR1BHTR6 | |
| SCHEMBL3928158 | 0.66 | PIK3CD (0.50) | GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034146-A1 | NOVEL ANTI-INFECTIVES | SMITHKLINE BEECHAM CORPORATION (US) | 2001-05-17 | — | — | WO | claimed |
| WO-2001034146-A1 | NOVEL ANTI-INFECTIVES | SMITHKLINE BEECHAM CORPORATION (US) | 2001-05-17 | — | — | WO | disclosed |