Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.36 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 2/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.32 |
| ▸ | ADK | P55263 | 1/20 | 0.32 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | RGS12 | O14924 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | RAD52 | P43351 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7399608 | 0.82 | MTNR1A (0.37) | MTNR1AMTNR1BALKGSK3BGSK3A | |
| SCHEMBL7396398 | 0.78 | FNTA (0.38) | MTNR1AMTNR1BMCL1ACMSDHTR6 | |
| SCHEMBL7403823 | 0.77 | MTNR1A (0.39) | MTNR1AMTNR1BGSK3BADKMCL1 | |
| SCHEMBL7392200 | 0.74 | MTNR1A (0.47) | MTNR1AMTNR1BHTR6ALDH1A1 | |
| SCHEMBL7396434 | 0.74 | MTNR1A (0.36) | MTNR1AMTNR1BMCL1ACMSDALDH1A1 | |
| SCHEMBL7398662 | 0.74 | MTNR1A (0.37) | MTNR1AMTNR1BGSK3BADKMCL1 | |
| SCHEMBL7401683 | 0.74 | HDAC6 (0.40) | MTNR1AMTNR1B | |
| SCHEMBL7306862 | 0.73 | HTR6 (0.35) | GSK3BGSK3AMCL1ACMSDHTR6 | |
| Hydrochloric Acid SCHEMBL7403768 | 0.65 | CA12 (0.42) | MTNR1AMTNR1BMCL1ACMSDHTR6 | |
| Hydrochloric Acid SCHEMBL7399520 | 0.65 | F2 (0.39) | MTNR1AMTNR1BMCL1ACMSDHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034146-A1 | NOVEL ANTI-INFECTIVES | SMITHKLINE BEECHAM CORPORATION (US) | 2001-05-17 | — | — | WO | claimed |
| WO-2001034146-A1 | NOVEL ANTI-INFECTIVES | SMITHKLINE BEECHAM CORPORATION (US) | 2001-05-17 | — | — | WO | disclosed |