Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 3/20 | 0.41 |
| ▸ | DPP4 | P27487 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 6/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL263092 | 0.82 | PNMT (0.44) | PNMTDPP4ALDH1A1LOXL2KDM4E | |
| Hydrochloric Acid SCHEMBL9624664 | 0.80 | PNMT (0.43) | PNMTDPP4ALDH1A1LOXL2KDM4E | |
| Hydrochloric Acid SCHEMBL8011172 | 0.80 | PNMT (0.43) | PNMTDPP4ALDH1A1LOXL2KDM4E | |
| SCHEMBL2072423 | 0.78 | GABRA1 (0.44) | ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL21808059 | 0.78 | GABRA1 (0.38) | ALDH1A1 | |
| SCHEMBL11796831 | 0.75 | ALDH1A1 (0.43) | ALDH1A1 | |
| SCHEMBL3595870 | 0.73 | PNMT (0.44) | PNMTDPP4LOXL2KDM4ESMN1; SMN2 | |
| SCHEMBL16542794 | 0.73 | PNMT (0.44) | PNMTDPP4LOXL2KDM4ESMN1; SMN2 | |
| SCHEMBL3146119 | 0.73 | LMNA (0.55) | PNMTDPP4ALDH1A1LOXL2KDM4E | |
| SCHEMBL16935678 | 0.73 | PNMT (0.44) | PNMTDPP4LOXL2KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0012401-A1 | Carboxyalkyl dipeptide derivatives, process for preparing them and pharmaceutical composition containing them | MERCK & CO. INC. (US) | 1980-06-25 | — | — | EP | disclosed |