SCHEMBL7396708

SCHEMBL7396708

CCOC[C@H](OC(=O)[C@H](C)CS)C(=O)O

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ENPEP Q07075 2/20 0.33
ACE P12821 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7396705 1.00 ENPEP (0.33) ENPEPACE
Amantadine SCHEMBL7390753 0.83 THRB (0.35)
Amantadine SCHEMBL7390749 0.83 THRB (0.35)
SCHEMBL7398554 0.81 ENPEP (0.34) ENPEP
SCHEMBL7398558 0.81 ENPEP (0.34) ENPEP
SCHEMBL7395739 0.79 MAPK1 (0.37) ENPEP
SCHEMBL7395742 0.79 MAPK1 (0.37) ENPEP
SCHEMBL7396987 0.78 MME (0.35) ACE
SCHEMBL7396991 0.78 MME (0.35) ACE
SCHEMBL7399559 0.78 LMNA (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0535042-B1 ANGIOTENSIS CONVERTING ENZYME INHIBITORS FISONS PLC (GB) 1995-03-29 EP claimed
US-5348978-A Angiotensin converting enzyme inhibitors FISONS PLC (GB) 1994-09-20 US claimed
EP-0535042-A1 ANGIOTENSIS CONVERTING ENZYME INHIBITORS. FISONS PLC (GB) 1993-04-07 EP claimed
WO-1992000276-A2 ANGIOTENSIS CONVERTING ENZYME INHIBITORS FISONS PLC (GB) 1992-01-09 WO claimed
US-5426161-A Reacting a phenolic novolak resin with trialkylamine; then a cyanogen bromide; cyclotrimerization ALLIEDSIGNAL INC. (US) 1995-06-20 US disclosed
EP-0345298-B1 CYANATO GROUP CONTAINING PHENOLIC RESINS, PHENOLIC TRIAZINES DERIVED THEREFROM AlliedSignal Inc. (US) 1993-08-11 EP disclosed
US-4978727-A HEAT, OXIDATION RESISTANCE; LONG SHELF-LIFE ALLIED-SIGNAL (US) 1990-12-18 US disclosed
EP-0345298-A1 CYANATO GROUP CONTAINING PHENOLIC RESINS, PHENOLIC TRIAZINES DERIVED THEREFROM. ALLIED CORP (US) 1989-12-13 EP disclosed
US-4771113-A INCREASED OXIDATIVE, MECHANICAL AND THERMAL STABILITY ALLIED CORPORATION (US) 1988-09-13 US disclosed
WO-1988005443-A2 CYANATO GROUP CONTAINING PHENOLIC RESINS, PHENOLIC TRIAZINES DERIVED THEREFROM ALLIED CORPORATION (US) 1988-07-28 WO disclosed
US-4757118-A Thermosettable modified phenolic polyester imide resins ALLIED CORPORATION (US) 1988-07-12 US disclosed
US-4650838-A OXIDATIVE, MECHANICAL AND THERMAL STABILITY ALLIED CORPORATION (US) 1987-03-17 US disclosed
US-4650839-A SELF-CROSSLINKING, OXIDATION AND HEAT RESISTANCE ALLIED CORPORATION (US) 1987-03-17 US disclosed