Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 2/20 | 0.50 |
| ▸ | TYR | P14679 | 1/20 | 0.46 |
| ▸ | TACR1 | P25103 | 3/20 | 0.46 |
| ▸ | CTSL | P07711 | 3/20 | 0.45 |
| ▸ | CTSB | P07858 | 3/20 | 0.45 |
| ▸ | CTSS | P25774 | 3/20 | 0.45 |
| ▸ | CTSK | P43235 | 3/20 | 0.45 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | PLAT | P00750 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7397381 | 0.83 | CTRB1 (0.54) | CTRB1TACR1CTSLCTSBCTSS | |
| SCHEMBL7352077 | 0.81 | TRPM8 (0.57) | CTRB1TACR1CTSLCTSBCTSS | |
| SCHEMBL3864222 | 0.79 | CTRB1 (0.59) | CTRB1TYRTACR1CTSLCTSB | |
| SCHEMBL13866599 | 0.79 | CTRB1 (0.59) | CTRB1TYRTACR1CTSLCTSB | |
| SCHEMBL3893048 | 0.79 | CTRB1 (0.59) | CTRB1TYRTACR1CTSLCTSB | |
| SCHEMBL18803174 | 0.78 | CTSL (0.52) | CTRB1TACR1CTSLCTSBCTSS | |
| SCHEMBL7345336 | 0.75 | ATM (0.59) | CTRB1CTSLCTSBCTSSCTSK | |
| SCHEMBL8022777 | 0.74 | LTA4H (0.54) | CTRB1TRPM8ATM | |
| SCHEMBL7398775 | 0.73 | ECE1 (0.52) | CTRB1CTSLCTSBCTSSCTSK | |
| SCHEMBL8026450 | 0.72 | LTA4H (0.53) | CTRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993011154-A1 | INHIBITORS OF THE CONVERSION OF BIG ENDOTHELIN TO ENDOTHELIN | BERLEX LABORATORIES, INC. (US) | 1993-06-10 | — | — | WO | claimed |
| US-5504070-A | ADMINISTERING OLIGOPEPTIDES, PHOSPHONATES AND MODIFIED AMINO ACIDS AS INHIBITORS | BERLEX LABORATORIES, INC. (US) | 1996-04-02 | — | — | US | disclosed |
| WO-1993011154-A1 | INHIBITORS OF THE CONVERSION OF BIG ENDOTHELIN TO ENDOTHELIN | BERLEX LABORATORIES, INC. (US) | 1993-06-10 | — | — | WO | disclosed |