Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPEP | Q07075 | 2/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.32 |
| ▸ | ECE1 | P42892 | 2/20 | 0.32 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7397931 | 1.00 | ENPEP (0.38) | ENPEPPRSS1TMPRSS15PTGS1SLC7A11 | |
| Amantadine SCHEMBL7401061 | 0.84 | THRB (0.37) | PRSS1TMPRSS15 | |
| Amantadine SCHEMBL7401055 | 0.84 | THRB (0.37) | PRSS1TMPRSS15 | |
| SCHEMBL7400541 | 0.81 | TSHR (0.36) | ENPEP | |
| SCHEMBL7400540 | 0.81 | TSHR (0.36) | ENPEP | |
| SCHEMBL7397737 | 0.81 | MMP1 (0.36) | ENPEP | |
| SCHEMBL7397741 | 0.81 | MMP1 (0.36) | ENPEP | |
| SCHEMBL7399838 | 0.79 | ENPEP (0.36) | ENPEPCYP1A2 | |
| SCHEMBL7399836 | 0.79 | ENPEP (0.36) | ENPEPCYP1A2 | |
| SCHEMBL7403311 | 0.78 | MME (0.36) | PRSS1TMPRSS15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0535042-B1 | ANGIOTENSIS CONVERTING ENZYME INHIBITORS | FISONS PLC (GB) | 1995-03-29 | — | — | EP | claimed |
| US-5348978-A | Angiotensin converting enzyme inhibitors | FISONS PLC (GB) | 1994-09-20 | — | — | US | claimed |
| EP-0535042-A1 | ANGIOTENSIS CONVERTING ENZYME INHIBITORS. | FISONS PLC (GB) | 1993-04-07 | — | — | EP | claimed |
| WO-1992000276-A2 | ANGIOTENSIS CONVERTING ENZYME INHIBITORS | FISONS PLC (GB) | 1992-01-09 | — | — | WO | claimed |