Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8458587 | 0.92 | SLC1A3 (0.47) | KDM4EALDH1A1SMN1; SMN2PKMSLC1A3 | |
| Hydrochloric Acid SCHEMBL7494945 | 0.85 | ITGB3 (0.44) | POLBALDH1A1SMN1; SMN2SLC1A3SLC1A2 | |
| SCHEMBL7398408 | 0.84 | ITGB3 (0.50) | MEN1KMT2ACYP1A2TSHRMAPT | |
| Hydrochloric Acid SCHEMBL7488066 | 0.83 | ITGB3 (0.59) | CYP3A4RAB9AMAPTITGB3ITGA2B | |
| SCHEMBL8454597 | 0.82 | ITGB3 (0.44) | ALDH1A1MEN1LMNAKMT2AGAA | |
| SCHEMBL7402176 | 0.82 | USP2 (0.44) | ALDH1A1MAPTCA2ITGB3ITGA2B | |
| SCHEMBL7402092 | 0.82 | ITGB3 (0.46) | POLBKDM4EALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL7398725 | 0.81 | ITGB3 (0.46) | KDM4ECYP2D6CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL7402108 | 0.81 | ITGB3 (0.60) | KDM4EALDH1A1LMNAPKMTSHR | |
| SCHEMBL7919384 | 0.80 | GAA (0.44) | POLBALDH1A1HPGDSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0673247-A4 | FIBRINOGEN RECEPTOR ANTAGONISTS. | MERCK & CO INC (US) | 1996-05-01 | — | — | EP | disclosed |
| EP-0673247-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO. INC. (US) | 1995-09-27 | — | — | EP | disclosed |
| WO-1994012181-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1994-06-09 | — | — | WO | disclosed |