Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 12/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 11/20 | 0.43 |
| ▸ | ITGAV | P06756 | 2/20 | 0.42 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | CTSG | P08311 | 1/20 | 0.38 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.38 |
| ▸ | CMA1 | P23946 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8801722 | 0.91 | MMP1 (0.44) | USP2ITGB3ITGA2BITGAVPSMB8 | |
| SCHEMBL7398408 | 0.89 | ITGB3 (0.50) | USP2ITGB3ITGA2BITGAVPSMB8 | |
| SCHEMBL8458438 | 0.88 | SLC1A3 (0.36) | USP2ITGB3ITGA2BITGAVPSMB8 | |
| SCHEMBL7487574 | 0.87 | ITGB3 (0.48) | ITGB3ITGA2BITGAVALDH1A1 | |
| SCHEMBL7484657 | 0.87 | ITGB3 (0.48) | ITGB3ITGA2BITGAVALDH1A1CA2 | |
| SCHEMBL7912610 | 0.86 | F2 (0.42) | ITGB3ITGA2BITGAVCA2 | |
| SCHEMBL8458587 | 0.84 | SLC1A3 (0.47) | ITGB3ITGA2BALDH1A1 | |
| SCHEMBL7398124 | 0.82 | POLB (0.45) | ITGB3ITGA2BMAPTALDH1A1CA2 | |
| SCHEMBL7920933 | 0.81 | ITGB3 (0.47) | ITGB3ITGA2BPRSS1CA2 | |
| SCHEMBL8455738 | 0.80 | GAA (0.42) | MAPTALDH1A1PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994012181-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1994-06-09 | — | — | WO | claimed |
| US-5648368-A | ANTICOAGULANTS | MERCK & CO., INC. (US) | 1997-07-15 | — | — | US | disclosed |
| WO-1994012181-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1994-06-09 | — | — | WO | disclosed |