Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 5/20 | 0.40 |
| ▸ | FCER2 | P06734 | 3/20 | 0.37 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.37 |
| ▸ | PTGFR | P43088 | 1/20 | 0.37 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.37 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 3/20 | 0.37 |
| ▸ | MMP3 | P08254 | 2/20 | 0.37 |
| ▸ | MMP7 | P09237 | 2/20 | 0.37 |
| ▸ | MMP9 | P14780 | 2/20 | 0.37 |
| ▸ | MMP8 | P22894 | 2/20 | 0.37 |
| ▸ | MMP13 | P45452 | 2/20 | 0.37 |
| ▸ | MMP14 | P50281 | 2/20 | 0.37 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7398653 | 1.00 | MMP1 (0.40) | MMP1FCER2PTGER1PTGFRPTGER3 | |
| Amantadine SCHEMBL7396703 | 0.87 | PTGER1 (0.36) | MMP1FCER2PTGER1PTGFRPTGER3 | |
| Amantadine SCHEMBL7396700 | 0.87 | PTGER1 (0.36) | MMP1FCER2PTGER1PTGFRPTGER3 | |
| SCHEMBL7399675 | 0.87 | MME (0.40) | MMP1FCER2PTGER1PTGFRPTGER3 | |
| SCHEMBL7399673 | 0.87 | MME (0.40) | MMP1FCER2PTGER1PTGFRPTGER3 | |
| SCHEMBL7394102 | 0.82 | MTNR1A (0.44) | ACEALDH1A1 | |
| SCHEMBL7394099 | 0.82 | MTNR1A (0.44) | ACEALDH1A1 | |
| SCHEMBL7393328 | 0.79 | MME (0.39) | ACEALDH1A1 | |
| SCHEMBL9240332 | 0.79 | MME (0.39) | ACEALDH1A1 | |
| SCHEMBL7396702 | 0.78 | ALDH1A1 (0.38) | MMP1PTGER1PTGFRPTGER3PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0535042-B1 | ANGIOTENSIS CONVERTING ENZYME INHIBITORS | FISONS PLC (GB) | 1995-03-29 | — | — | EP | claimed |
| EP-0535042-A1 | ANGIOTENSIS CONVERTING ENZYME INHIBITORS. | FISONS PLC (GB) | 1993-04-07 | — | — | EP | claimed |
| WO-1992000276-A2 | ANGIOTENSIS CONVERTING ENZYME INHIBITORS | FISONS PLC (GB) | 1992-01-09 | — | — | WO | claimed |