Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.39 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6859545 | 0.81 | TSHR (0.52) | TSHRMGLLL3MBTL1TDP1CA1 | |
| SCHEMBL4543170 | 0.81 | CA2 (0.46) | TSHRMGLLL3MBTL1TDP1CA1 | |
| SCHEMBL21068846 | 0.79 | CA2 (0.45) | TSHRMGLLL3MBTL1TDP1CA1 | |
| SCHEMBL27461085 | 0.79 | TSHR (0.45) | TSHRMGLLL3MBTL1TDP1CA1 | |
| Trifluoromethanesulfonic Acid SCHEMBL4543174 | 0.78 | TSHR (0.41) | TSHRMGLLL3MBTL1TDP1PTPN2 | |
| SCHEMBL29990163 | 0.78 | TSHR (0.48) | TSHRMGLLL3MBTL1TDP1CA1 | |
| SCHEMBL1002697 | 0.78 | CA2 (0.52) | TSHRMGLLL3MBTL1TDP1CA1 | |
| SCHEMBL7195587 | 0.78 | TSHR (0.48) | TSHRMGLLL3MBTL1TDP1CA1 | |
| SCHEMBL2086018 | 0.78 | TSHR (0.48) | TSHRMGLLL3MBTL1TDP1CA1 | |
| SCHEMBL8552660 | 0.78 | KCNA3 (0.52) | MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0618926-B1 | NEW PEPTIDE DERIVATIVES | ASTRA AB (SE) | 2000-03-01 | — | — | EP | disclosed |
| US-5955433-A | DERIVATIVES OF B-CYCLOHEXYLALANINE-PROLINE-AGMATINE ARE ADMINISTERED AS ANTICOAGULANTS | ASTRA AKTIEBOLAG (SE) | 1999-09-21 | — | — | US | disclosed |
| US-5747460-A | Method of treatment and prophylaxis of venous thrombosis | ASTRA AKTIEBOLAG (SE) | 1998-05-05 | — | — | US | disclosed |
| US-5614499-A | ANTICOAGULANTS; TREATMENT OR PROPHYLAXIS OF THROMBOSIS | ASTRA AKTIEBOLAG (SE) | 1997-03-25 | — | — | US | disclosed |
| EP-0618926-A1 | NEW PEPTIDE DERIVATIVES | Astra Aktiebolag (SE) | 1994-10-12 | — | — | EP | disclosed |
| WO-1993011152-A1 | NEW PEPTIDE DERIVATIVES | AKTIEBOLAGET ASTRA (SE) | 1993-06-10 | — | — | WO | disclosed |