Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | FPR2 | P25090 | 4/20 | 0.46 |
| ▸ | CASR | P41180 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.46 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7370963 | 0.94 | L3MBTL1 (0.52) | ALDH1A1MAPTLMNAL3MBTL1HDAC1 | |
| SCHEMBL7398744 | 0.87 | ALDH1A1 (0.49) | ALDH1A1LMNAHDAC1HDAC8SMN1; SMN2 | |
| SCHEMBL7393732 | 0.87 | PKM (0.58) | ALDH1A1MAPTLMNAHDAC1HDAC8 | |
| SCHEMBL7400935 | 0.86 | CNR1 (0.50) | ALDH1A1HDAC1HDAC8CNR1HDAC2 | |
| SCHEMBL7397884 | 0.86 | HDAC1 (0.62) | ALDH1A1LMNAHDAC1HDAC8HDAC2 | |
| SCHEMBL7366506 | 0.82 | KMT2A (0.47) | LMNAHDAC1HDAC8CNR1HDAC2 | |
| SCHEMBL7373364 | 0.82 | HDAC1 (0.60) | ALDH1A1LMNAHDAC1HDAC8HDAC2 | |
| SCHEMBL20708118 | 0.82 | SMN1; SMN2 (0.68) | ALDH1A1LMNAL3MBTL1SMN1; SMN2FPR2 | |
| SCHEMBL7368829 | 0.81 | PKM (0.64) | ALDH1A1MAPTLMNAHDAC1HDAC8 | |
| SCHEMBL7367523 | 0.81 | ALDH1A1 (0.54) | ALDH1A1LMNAHDAC1HDAC8SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002046129-A2 | INHIBITORS OF HISTONE DEACETYLASE | ABBOTT LABORATORIES (US) | 2002-06-13 | — | — | WO | disclosed |