Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 7/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7368807 | 0.94 | CNR1 (0.56) | CNR1SLC6A3HDAC1HDAC2HDAC3 | |
| SCHEMBL7398744 | 0.89 | ALDH1A1 (0.49) | CNR1SLC6A3HDAC1HDAC2HDAC3 | |
| SCHEMBL7397884 | 0.88 | HDAC1 (0.62) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL7399200 | 0.86 | ALDH1A1 (0.47) | CNR1HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL7367523 | 0.83 | ALDH1A1 (0.54) | CNR1SLC6A3HDAC1HDAC2HDAC3 | |
| SCHEMBL7373503 | 0.81 | HDAC1 (0.70) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL7370963 | 0.80 | L3MBTL1 (0.52) | CNR1HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL7364670 | 0.80 | HDAC1 (0.70) | CNR1HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL11048686 | 0.79 | CNR1 (0.70) | CNR1SLC6A3EPHX1 | |
| SCHEMBL7393732 | 0.78 | PKM (0.58) | CNR1HDAC1HDAC2HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002046129-A2 | INHIBITORS OF HISTONE DEACETYLASE | ABBOTT LABORATORIES (US) | 2002-06-13 | — | — | WO | disclosed |