Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7392857 | 0.83 | RAB9A (0.49) | AMY1AKDM4ERAB9ANPC1ALDH1A1 | |
| SCHEMBL7992209 | 0.81 | AMY1A (0.43) | AMY1AKDM4ERAB9ANPC1ALDH1A1 | |
| SCHEMBL7399325 | 0.81 | RAB9A (0.47) | AMY1AKDM4ERAB9ANPC1ALDH1A1 | |
| SCHEMBL7396331 | 0.77 | KDM4E (0.53) | AMY1AKDM4ERAB9ANPC1ALDH1A1 | |
| SCHEMBL7397419 | 0.76 | KDM4E (0.52) | AMY1AKDM4ERAB9ANPC1ALDH1A1 | |
| SCHEMBL7390002 | 0.76 | AMY1A (0.58) | AMY1AKDM4ERAB9ANPC1ALDH1A1 | |
| SCHEMBL7395552 | 0.75 | PARP1 (0.59) | AMY1AKDM4ERAB9ANPC1ALDH1A1 | |
| SCHEMBL7392370 | 0.74 | AMY1A (0.46) | AMY1AKDM4ERAB9ANPC1ALDH1A1 | |
| SCHEMBL7396509 | 0.74 | AMY1A (0.75) | AMY1AKDM4ERAB9ANPC1ALDH1A1 | |
| SCHEMBL7389936 | 0.72 | KDM4E (0.62) | KDM4ERAB9ANPC1ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001066526-A1 | ESTER DERIVATIVES OF DIMETHYLPROPIONIC ACID AND PHARMACETUICAL COMPOSITIONS CONTAINING THEM | CERMOL S.A. (CH) | 2001-09-13 | — | — | WO | claimed |
| EP-1132381-A1 | Ester derivatives of dimethylpropionic acid and pharmaceutical compositions containing them | CERMOL S.A. (CH) | 2001-09-12 | — | — | EP | claimed |
| WO-2001066526-A1 | ESTER DERIVATIVES OF DIMETHYLPROPIONIC ACID AND PHARMACETUICAL COMPOSITIONS CONTAINING THEM | CERMOL S.A. (CH) | 2001-09-13 | — | — | WO | disclosed |
| EP-1132381-A1 | Ester derivatives of dimethylpropionic acid and pharmaceutical compositions containing them | CERMOL S.A. (CH) | 2001-09-12 | — | — | EP | disclosed |