Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 7/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SLCO1B1 | Q9Y6L6 | 2/20 | 0.42 |
| ▸ | ACACB | O00763 | 3/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7399544 | 0.87 | ALDH1A1 (0.46) | ITGB3ITGA2BHRH3ALDH1A1GAA | |
| SCHEMBL7402061 | 0.85 | HRH3 (0.48) | FFAR4ITGB3ITGA2BHRH3ALDH1A1 | |
| SCHEMBL7399602 | 0.85 | FFAR4 (0.48) | FFAR4HRH3ALDH1A1 | |
| SCHEMBL7400365 | 0.77 | ITGB3 (0.48) | FFAR4ITGB3ITGA2BHRH3ACACB | |
| SCHEMBL10188580 | 0.76 | FFAR4 (0.52) | FFAR4 | |
| SCHEMBL22252621 | 0.75 | FFAR4 (0.50) | FFAR4HRH3SLCO1B1 | |
| SCHEMBL22463663 | 0.75 | PARP10 (0.46) | FFAR4SLCO1B1 | |
| SCHEMBL22252517 | 0.75 | FFAR4 (0.50) | FFAR4HRH3SLCO1B1 | |
| SCHEMBL22578254 | 0.75 | PARP10 (0.46) | FFAR4SLCO1B1 | |
| SCHEMBL22256603 | 0.75 | FFAR4 (0.50) | FFAR4HRH3SLCO1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0690847-A1 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1996-01-10 | — | — | EP | disclosed |
| WO-1994022835-A2 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1994-10-13 | — | — | WO | disclosed |