Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ACACB | O00763 | 8/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7399368 | 0.87 | FFAR4 (0.46) | ALDH1A1GAAACACBITGB3ITGA2B | |
| SCHEMBL7398139 | 0.86 | ALDH1A1 (0.49) | ALDH1A1GAAACACBMAPTITGB3 | |
| SCHEMBL5759922 | 0.76 | MAPT (0.62) | ALDH1A1MAPTITGB3ITGA2BHRH3 | |
| SCHEMBL21673845 | 0.75 | LATS1 (0.43) | ALDH1A1ACACBMAPTKMT2A | |
| SCHEMBL7402061 | 0.75 | HRH3 (0.48) | ALDH1A1GAAACACBITGB3ITGA2B | |
| SCHEMBL31401390 | 0.74 | KDM4E (0.46) | ALDH1A1MAPTHIF1ASMN1; SMN2MEN1 | |
| SCHEMBL22252465 | 0.74 | P2RX7 (0.54) | MAPT | |
| SCHEMBL7399602 | 0.73 | FFAR4 (0.48) | ALDH1A1HRH3SMN1; SMN2KMT2A | |
| SCHEMBL8201212 | 0.73 | ACACB (0.41) | ACACBSMN1; SMN2 | |
| SCHEMBL7400365 | 0.72 | ITGB3 (0.48) | ACACBITGB3ITGA2BHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563141-A | INHIBIT CELL ADHESION FOR EXAMPLE, PLATELET AGGRE GATION | ZENECA LIMITED (GB) | 1996-10-08 | — | — | US | disclosed |
| EP-0690847-A1 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1996-01-10 | — | — | EP | disclosed |
| WO-1994022835-A2 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1994-10-13 | — | — | WO | disclosed |