Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 6/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.43 |
| ▸ | CPT2 | P23786 | 1/20 | 0.42 |
| ▸ | CPT1A | P50416 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7399368 | 0.85 | FFAR4 (0.46) | FFAR4HRH3ALDH1A1 | |
| SCHEMBL7402721 | 0.78 | FFAR1 (0.55) | FFAR4FFAR1HRH3KDM4EALDH1A1 | |
| SCHEMBL7398640 | 0.77 | GPR119 (0.45) | FFAR4FFAR1HRH3GRM1KDM4E | |
| SCHEMBL10188580 | 0.76 | FFAR4 (0.52) | FFAR4 | |
| SCHEMBL7399544 | 0.73 | ALDH1A1 (0.46) | HRH3ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL7403804 | 0.73 | FFAR1 (0.44) | FFAR4FFAR1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL7403806 | 0.73 | GPR119 (0.46) | FFAR4FFAR1HRH3KDM4EALDH1A1 | |
| SCHEMBL2274636 | 0.73 | KDM4E (0.66) | KDM4EALDH1A1HSD17B10GPR119MAPK1 | |
| SCHEMBL3778359 | 0.72 | HRH3 (0.50) | FFAR4FFAR1HRH3KDM4EALDH1A1 | |
| SCHEMBL20004100 | 0.71 | FFAR1 (0.51) | FFAR1HRH3KDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563141-A | INHIBIT CELL ADHESION FOR EXAMPLE, PLATELET AGGRE GATION | ZENECA LIMITED (GB) | 1996-10-08 | — | — | US | disclosed |
| EP-0690847-A1 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1996-01-10 | — | — | EP | disclosed |
| WO-1994022835-A2 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1994-10-13 | — | — | WO | disclosed |