Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 12/20 | 0.49 |
| ▸ | CTSS | P25774 | 11/20 | 0.49 |
| ▸ | CTSB | P07858 | 11/20 | 0.49 |
| ▸ | CTSK | P43235 | 11/20 | 0.49 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7394745 | 0.80 | CTSL (0.59) | CTSLCTSSCTSBCTSK | |
| SCHEMBL4711786 | 0.76 | CTSK (0.69) | CTSLCTSSCTSBCTSK | |
| SCHEMBL7397511 | 0.76 | CTSL (0.51) | CTSLCTSSCTSBCTSK | |
| SCHEMBL7446518 | 0.76 | CTSL (0.64) | CTSLCTSSCTSBCTSK | |
| SCHEMBL7436831 | 0.74 | CTSL (0.64) | CTSLCTSSCTSBCTSK | |
| SCHEMBL7405812 | 0.70 | CTSK (0.62) | CTSLCTSSCTSBCTSKAOC3 | |
| SCHEMBL4701852 | 0.68 | CTSK (0.69) | CTSLCTSSCTSBCTSK | |
| SCHEMBL7442354 | 0.67 | CTSL (0.48) | CTSLCTSSCTSBCTSK | |
| SCHEMBL7439946 | 0.67 | CTSK (0.51) | CTSLCTSSCTSBCTSKAOC3 | |
| SCHEMBL7404362 | 0.66 | CTSK (0.50) | CTSLCTSSCTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001049288-A9 | NOVEL COMPOUNDS AND COMPOSITIONS AS PROTEASE INHIBITORS | MERCK FROSST CANADA INC (CA) | 2001-10-25 | — | — | WO | claimed |