Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 10/20 | 0.50 |
| ▸ | CTSL | P07711 | 5/20 | 0.50 |
| ▸ | CTSB | P07858 | 7/20 | 0.47 |
| ▸ | CTSS | P25774 | 7/20 | 0.46 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.43 |
| ▸ | AGXT | P21549 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.40 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.40 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7447450 | 0.96 | CTSK (0.54) | CTSKCTSLCTSBCTSSPRKD1 | |
| SCHEMBL7405812 | 0.89 | CTSK (0.62) | CTSKCTSLCTSBCTSSPRKD1 | |
| SCHEMBL7442354 | 0.89 | CTSL (0.48) | CTSKCTSLCTSBCTSSAGXT | |
| SCHEMBL7397511 | 0.85 | CTSL (0.51) | CTSKCTSLCTSBCTSS | |
| SCHEMBL7439946 | 0.85 | CTSK (0.51) | CTSKCTSLCTSBCTSS | |
| SCHEMBL7401645 | 0.81 | CTSL (0.60) | CTSKCTSLCTSBCTSSPRKD1 | |
| SCHEMBL7398927 | 0.79 | CTSK (0.63) | CTSKCTSLCTSBCTSSPRKD1 | |
| SCHEMBL7394745 | 0.79 | CTSL (0.59) | CTSKCTSLCTSBCTSS | |
| SCHEMBL7451409 | 0.76 | CTSB (0.53) | CTSKCTSLCTSBCTSSPRKD1 | |
| SCHEMBL7444865 | 0.76 | CTSK (0.39) | CTSKCTSLCTSBCTSSPRKD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001049288-A9 | NOVEL COMPOUNDS AND COMPOSITIONS AS PROTEASE INHIBITORS | MERCK FROSST CANADA INC (CA) | 2001-10-25 | — | — | WO | claimed |
| WO-2001049288-A9 | NOVEL COMPOUNDS AND COMPOSITIONS AS PROTEASE INHIBITORS | MERCK FROSST CANADA INC (CA) | 2001-10-25 | — | — | WO | disclosed |