Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 11/20 | 0.64 |
| ▸ | CTSB | P07858 | 11/20 | 0.64 |
| ▸ | CTSS | P25774 | 11/20 | 0.64 |
| ▸ | CTSK | P43235 | 9/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7446518 | 0.96 | CTSL (0.64) | CTSLCTSBCTSSCTSKMAPT | |
| SCHEMBL7398927 | 0.91 | CTSK (0.63) | CTSLCTSBCTSSCTSKMEN1 | |
| SCHEMBL7401645 | 0.90 | CTSL (0.60) | CTSLCTSBCTSSCTSKMEN1 | |
| SCHEMBL7397511 | 0.83 | CTSL (0.51) | CTSLCTSBCTSSCTSK | |
| SCHEMBL7394745 | 0.83 | CTSL (0.59) | CTSLCTSBCTSSCTSK | |
| SCHEMBL4716426 | 0.78 | CTSK (1.00) | CTSLCTSBCTSSCTSK | |
| SCHEMBL7392893 | 0.78 | CTSL (0.55) | CTSLCTSBCTSSCTSKMEN1 | |
| SCHEMBL7399686 | 0.74 | CTSS (0.47) | CTSLCTSBCTSSCTSK | |
| SCHEMBL7399397 | 0.74 | CTSL (0.49) | CTSLCTSBCTSSCTSK | |
| SCHEMBL4714257 | 0.74 | CTSL (1.00) | CTSLCTSBCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001049288-A9 | NOVEL COMPOUNDS AND COMPOSITIONS AS PROTEASE INHIBITORS | MERCK FROSST CANADA INC (CA) | 2001-10-25 | — | — | WO | claimed |