SCHEMBL739949

SCHEMBL739949

COc1ccc(SSc2ccc(OC)c(N=C=O)c2)cc1N=C=O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.53
CYP3A4 P08684 4/20 0.53
HPGD P15428 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
TRPA1 O75762 1/20 0.36
AR P10275 5/20 0.33
MAPT P10636 2/20 0.33
LMNA P02545 3/20 0.32
TSHR P16473 4/20 0.31
CA1 P00915 2/20 0.31
CA2 P00918 2/20 0.31
CA7 P43166 2/20 0.31
CA9 Q16790 2/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
POLB P06746 1/20 0.31
MAPK1 P28482 1/20 0.31
ACHE P22303 1/20 0.31
CA12 O43570 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29466688 1.00 ALDH1A1 (0.53) ALDH1A1CYP3A4HPGDTDP1TRPA1
SCHEMBL740984 0.86 ALDH1A1 (0.67) ALDH1A1CYP3A4HPGDTDP1TRPA1
SCHEMBL2142308 0.83 APLNR (0.39) ALDH1A1CYP3A4HPGDTDP1AR
SCHEMBL9623542 0.82 HPGD (0.38) ALDH1A1CYP3A4HPGDTDP1TRPA1
SCHEMBL5891689 0.80 CYP3A4 (0.73) ALDH1A1CYP3A4HPGDTDP1TRPA1
SCHEMBL124245 0.79 CYP3A4 (0.59) ALDH1A1CYP3A4HPGDTDP1TRPA1
SCHEMBL29538723 0.79 ALDH1A1 (0.56) ALDH1A1CYP3A4HPGDTDP1MAPT
SCHEMBL29510769 0.79 CYP3A4 (0.59) ALDH1A1CYP3A4HPGDTDP1TRPA1
SCHEMBL29648847 0.79 CYP3A4 (0.56) ALDH1A1CYP3A4HPGDTDP1TRPA1
SCHEMBL1019299 0.79 CYP3A4 (0.56) ALDH1A1CYP3A4HPGDTDP1TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 554 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12606692-B2 Spectacle lens HOYA LENS THAILAND LTD. (TH) 2026-04-21 US disclosed
EP-3983466-B1 AQUEOUS POLYURETHANE DISPERSION COVESTRO DEUTSCHLAND AG (DE) 2026-02-18 EP disclosed
EP-3778170-B1 METHOD FOR MANUFACTURING OPTICAL MEMBER HOYA LENS THAILAND LTD (TH) 2026-01-28 EP disclosed
US-12384124-B2 Method for producing polarizing lens, polarizing film and polarizing lens HOYA LENS THAILAND LTD. (TH) 2025-08-12 US disclosed
EP-4396248-B1 AQUEOUS POLYURETHANE-UREA DISPERSION COVESTRO DEUTSCHLAND AG (DE) 2025-08-06 EP disclosed
EP-3689932-B1 METHOD FOR MANUFACTURING OPTICAL MEMBER RESIN, OPTICAL MEMBER RESIN, SPECTACLE LENS, AND SPECTACLES HOYA LENS THAILAND LTD (TH) 2025-07-30 EP disclosed
US-12359016-B2 Method of preparing low haze polymer compositions for use in high refractive index optical materials PPG INDUSTRIES OHIO, INC. (US) 2025-07-15 US disclosed
US-20250188215-A1 AQUEOUS POLYURETHANE DISPERSION COVESTRO DEUTSCHLAND AG (DE) 2025-06-12 US disclosed
US-20250188024-A1 METHOD OF PRODUCING PENTAERYTHRITOL MERCAPTOCARBOXYLATE, POLYMERIZABLE COMPOSITION, RESIN, OPTICAL MATERIAL, AND SPECTACLE LENS HOYA LENS THAILAND LTD. (TH) 2025-06-12 US disclosed
US-20250179014-A1 METHOD OF PRODUCING PENTAERYTHRITOL MERCAPTOCARBOXYLATE, POLYMERIZABLE COMPOSITION, RESIN, OPTICAL MATERIAL, AND SPECTACLE LENS HOYA LENS THAILAND LTD. (TH) 2025-06-05 US disclosed
EP-0506315-A2 Optical urethane resins and plastic lenses comprising the same MITSUI TOATSU CHEMICALS, Inc. (JP) 1992-09-30 EP disclosed
EP-0505150-A1 Stabilizing method of isocyanate compounds and isocyanate compositions stabilized thereby MITSUI TOATSU CHEMICALS, Inc. (JP) 1992-09-23 EP disclosed
US-5126388-A Sulfur-containing polyurethane or polythiourethane and internal mold release agent MITSUI TOATSU CHEMICALS, INC. (JP) 1992-06-30 US disclosed
US-5087758-A Polythiourethane monomer MITSUI TOATSU CHEMICALS, INC. (JP) 1992-02-11 US disclosed
US-5013496-A Polyurethane or polythiourethane MITSUI TOATSU CHEMICALS, INC. (JP) 1991-05-07 US disclosed
US-4946923-A S-alkyl thiocarbamate base resin, plastic lens comprising the resin, and process for making the lens MITSUI TOATSU CHEMICALS, INC. (JP) 1990-08-07 US disclosed
EP-0378895-A1 A mercapto compound, a high refractive index resin and lens and a process for preparing them MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-07-25 EP disclosed
US-4929707-A Polyurethane base lens resin, plastic lens comprising the resin and preparation method of the lens MITSUI TOATSU CHEMICALS, INC. (JP) 1990-05-29 US disclosed
EP-0330363-A2 Highly-refractive plastic lens and process for making the lens MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-08-30 EP disclosed
EP-0329389-A2 Polyurethane base lens and its preparation method MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-08-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12606692-B2 Spectacle lens POT1, TCOF1, CRY1 ALDH1A1 2689/4885CYP3A4 4631/4885HPGD 3959/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.