Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.41 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.40 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | FABP4 | P15090 | 1/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.39 |
| ▸ | WNT3A | P56704 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23041398 | 0.86 | LMNA (0.48) | LMNAGAATAS2R14KCNK3KCNK9 | |
| SCHEMBL1195140 | 0.84 | TAS2R14 (0.51) | LMNAGAATAS2R14KCNK3KCNK9 | |
| SCHEMBL3108190 | 0.82 | LMNA (0.46) | LMNAGAATAS2R14KCNK3KCNK9 | |
| SCHEMBL634076 | 0.82 | PARP1 (0.47) | LMNAGAATAS2R14KCNK3KCNK9 | |
| SCHEMBL28484672 | 0.82 | TAS2R14 (0.50) | LMNAGAATAS2R14KCNK3KCNK9 | |
| SCHEMBL2001643 | 0.82 | LMNA (0.46) | LMNAGAATAS2R14KCNK3KCNK9 | |
| SCHEMBL2189933 | 0.82 | LMNA (0.46) | LMNAGAATAS2R14KCNK3KCNK9 | |
| SCHEMBL30554614 | 0.82 | PARP1 (0.47) | LMNAGAATAS2R14KCNK3KCNK9 | |
| SCHEMBL2195147 | 0.81 | LMNA (0.62) | LMNAGAAKCNK3KCNK9PTGS1 | |
| SCHEMBL20561313 | 0.81 | LMNA (0.44) | LMNAGAATAS2R14KCNK3KCNK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1212295-A1 | SUBSTITUTED $g(a)-HYDROXY ACID CASPASE INHIBITORS AND THE USE THEREOF | Cytovia, Inc. (US) | 2002-06-12 | — | — | EP | disclosed |
| WO-2001016093-A1 | SUBSTITUTED α-HYDROXY ACID CASPASE INHIBITORS AND THE USE THEREOF | CYTOVIA, INC. (US) | 2001-03-08 | — | — | WO | disclosed |