Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.50 |
| ▸ | WNT3A | P56704 | 3/20 | 0.50 |
| ▸ | CNR2 | P34972 | 2/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.46 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | PPIA | P62937 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL746794 | 0.84 | LMNA (0.64) | LMNAGAACTNNB1WNT3ACNR2 | |
| SCHEMBL28634751 | 0.84 | LMNA (0.64) | LMNAGAACTNNB1WNT3ACNR2 | |
| SCHEMBL28815055 | 0.82 | LMNA (0.62) | LMNAGAACTNNB1WNT3ACNR2 | |
| SCHEMBL30449216 | 0.82 | LMNA (0.62) | LMNAGAACTNNB1WNT3ACNR2 | |
| SCHEMBL221518 | 0.82 | LMNA (0.62) | LMNAGAACTNNB1WNT3ACNR2 | |
| SCHEMBL5794560 | 0.82 | LMNA (0.62) | LMNAGAACTNNB1WNT3ACNR2 | |
| SCHEMBL7399514 | 0.81 | LMNA (0.47) | LMNAGAACTNNB1WNT3ACNR2 | |
| SCHEMBL2307603 | 0.80 | LMNA (0.60) | LMNAGAACTNNB1WNT3ACNR2 | |
| Hydrochloric Acid SCHEMBL2533965 | 0.80 | LMNA (0.60) | LMNAGAACTNNB1WNT3ACNR2 | |
| SCHEMBL513651 | 0.80 | LMNA (0.60) | LMNAGAACTNNB1WNT3ACNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160185743-A1 | 15-Oxospiramilactone Derivatives, Preparation Method and Uses Thereof | CENTER FOR EXCELLENCE IN MOLECULAR CELL SCIENCE, CHINESE ACADEMY OF SCIENCES (CN) | 2016-06-30 | — | — | US | claimed |
| US-20150322094-A1 | USE OF SUBSTITUTED 2,3-DIHYDRO-1-BENZOFURAN-4-CARBOXYLIC ACIDS OR SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS | BAYER CROPSCIENCE AG (DE) | 2015-11-12 | — | — | US | claimed |
| EP-2892343-A1 | USE OF SUBSTITUTED 2,3-DIHYDRO-1-BENZOFURAN-4-CARBOXYLIC ACIDS OR SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS | Bayer CropScience AG (DE) | 2015-07-15 | — | — | EP | claimed |
| WO-2014037349-A1 | USE OF SUBSTITUTED 2,3-DIHYDRO-1-BENZOFURAN-4-CARBOXYLIC ACIDS OR SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS | BAYER CROPSCIENCE AG (DE) | 2014-03-13 | — | — | WO | claimed |
| EP-0649846-B1 | Galanthamine derivates, a process for their preparation and their use as medicaments | AVENTIS PHARMA INC (US) | 2002-01-02 | — | — | EP | claimed |
| US-6316439-B1 | TREATING MEMORY DYSFUNCTION | AVENTIS PHARAMACEUTICALS INC. | 2001-11-13 | — | — | US | claimed |
| EP-0649846-A1 | Galanthamine derivates, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1995-04-26 | — | — | EP | claimed |
| WO-2023210623-A1 | HALOALKYL SULFONE ANILIDE COMPOUND AND HERBICIDE CONTAINING SAME | 株式会社エス・ディー・エス バイオテック | 2023-11-02 | — | — | WO | disclosed |
| US-10112918-B2 | 15-oxospiramilactone derivatives, preparation method and uses thereof | KUNMING INSTITUTE OF BOTANY, THE CHINESE ACADEMY OF SCIENCES (CN) | 2018-10-30 | — | — | US | disclosed |
| US-20160185743-A1 | 15-Oxospiramilactone Derivatives, Preparation Method and Uses Thereof | CENTER FOR EXCELLENCE IN MOLECULAR CELL SCIENCE, CHINESE ACADEMY OF SCIENCES (CN) | 2016-06-30 | — | — | US | disclosed |
| US-20150322094-A1 | USE OF SUBSTITUTED 2,3-DIHYDRO-1-BENZOFURAN-4-CARBOXYLIC ACIDS OR SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS | BAYER CROPSCIENCE AG (DE) | 2015-11-12 | — | — | US | disclosed |
| US-20150315146-A1 | USE OF SUBSTITUTED 1-(ARYL ETHYNYL)-, 1-(HETEROARYL ETHYNYL)-, 1-(HETEROCYCLYL ETHYNYL)- AND 1-(CYCLOALKENYLETHYNYL)-BICYCLOALKANOLS AS ACTIVE AGENTS AGAINST ABIOTIC PLANT STRESS | BAYER CROPSCIENCE AG (DE) | 2015-11-05 | — | — | US | disclosed |
| US-20150305334-A1 | USE OF SUBSTITUTED 1-(ARYL ETHYNYL)-, 1-(HETEROARYL ETHYNYL)-, 1-(HETEROCYCLYL ETHYNYL)- AND 1-(CYCLOALKENYL ETHYNYL)-CYCLOHEXANOLS AS ACTIVE AGENTS AGAINST ABIOTIC PLANT STRESS | BAYER CROPSCIENCE AG (DE) | 2015-10-29 | — | — | US | disclosed |
| US-6509480-B2 | 4,7,8 alpha H-eudesma-5(6), 11(13)-dien-8, 12-olide derivatives | ALTEON, INC. | 2003-01-21 | — | — | US | disclosed |
| US-20020151581-A1 | Glucose and lipid lowering compounds | SYNVISTA THERAPEUTICS, INC. | 2002-10-17 | — | — | US | disclosed |
| US-6326396-B1 | ACID OR AMIDE COMPOUND ON HYDRONAPHTHALENE COMPOUND | ALTEON, INC. | 2001-12-04 | — | — | US | disclosed |
| EP-1135119-A1 | GLUCOSE AND LIPID LOWERING COMPOUNDS | ALTEON, INC. (US) | 2001-09-26 | — | — | EP | disclosed |
| WO-2000027388-A1 | GLUCOSE AND LIPID LOWERING COMPOUNDS | ALTEON, INC. (US) | 2000-05-18 | — | — | WO | disclosed |
| US-5262385-A | Pyrimidine ring containing | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1993-11-16 | — | — | US | disclosed |
| EP-0468766-A1 | Halogen-containing compounds, herbicidal composition containing the same as an active ingredient, and intermediary compounds therefor | Mitsubishi Chemical Corporation (JP) | 1992-01-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160185743-A1 | 15-Oxospiramilactone Derivatives, Preparation Method and Uses Thereof | WNT1, WNT3, WNT3A | LMNA 2160/4885GAA 3423/4885CTNNB1 6/4885 |
| US-20150322094-A1 | USE OF SUBSTITUTED 2,3-DIHYDRO-1-BENZOFURAN-4-CARBOXYLIC ACIDS OR SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS | CAT, HSF1, HPD | LMNA 4642/4885GAA 170/4885CTNNB1 4103/4885 |
| US-10112918-B2 | 15-oxospiramilactone derivatives, preparation method and uses thereof | WNT1, WNT3, WNT3A | LMNA 2160/4885GAA 3423/4885CTNNB1 6/4885 |
| US-20150315146-A1 | USE OF SUBSTITUTED 1-(ARYL ETHYNYL)-, 1-(HETEROARYL ETHYNYL)-, 1-(HETEROCYCLYL ETHYNYL)- AND 1-(CYCLOALKENYLETHYNYL)-BICYCLOALKANOLS AS ACTIVE AGENTS AGAINST ABIOTIC PLANT STRESS | AAK1, SYMPK, CBR1 | LMNA 4449/4885GAA 1336/4885CTNNB1 3804/4885 |
| US-20150305334-A1 | USE OF SUBSTITUTED 1-(ARYL ETHYNYL)-, 1-(HETEROARYL ETHYNYL)-, 1-(HETEROCYCLYL ETHYNYL)- AND 1-(CYCLOALKENYL ETHYNYL)-CYCLOHEXANOLS AS ACTIVE AGENTS AGAINST ABIOTIC PLANT STRESS | CBR1, CAT, NAT1 | LMNA 4532/4885GAA 667/4885CTNNB1 3154/4885 |
| US-20020151581-A1 | Glucose and lipid lowering compounds | HMGCR, APOB, SREBF1 | LMNA 1061/4885GAA 559/4885CTNNB1 1483/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.