Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.50 |
| ▸ | DRD2 | P14416 | 3/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.49 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7402389 | 0.96 | DRD4 (0.53) | DRD4SLC6A4ITGB3ITGA2BDRD2 | |
| SCHEMBL9080272 | 0.87 | HRH3 (0.51) | DRD2HRH3CACNA1GHTR2AHTR2C | |
| SCHEMBL8635007 | 0.87 | DRD4 (0.60) | DRD4SLC6A4ITGB3ITGA2BHRH3 | |
| Hydrochloric Acid SCHEMBL27454125 | 0.86 | DRD4 (0.58) | DRD4SLC6A4ITGB3ITGA2BHRH3 | |
| SCHEMBL7397112 | 0.84 | HTR1A (0.54) | DRD4SLC6A4DRD2HRH3HTR1A | |
| Hydrochloric Acid SCHEMBL9023742 | 0.82 | DRD4 (0.60) | DRD4SLC6A4ITGB3ITGA2BHRH3 | |
| SCHEMBL8837987 | 0.81 | ITGB3 (0.63) | DRD4SLC6A4ITGB3ITGA2BDRD2 | |
| SCHEMBL7402710 | 0.77 | DRD2 (0.59) | ITGB3ITGA2BDRD2 | |
| SCHEMBL11436565 | 0.76 | LMNA (0.65) | DRD4DRD2DRD3HTR2AHTR1A | |
| Bicarbonate SCHEMBL9023141 | 0.76 | DRD2 (0.48) | DRD4SLC6A4DRD2DRD3HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563141-A | INHIBIT CELL ADHESION FOR EXAMPLE, PLATELET AGGRE GATION | ZENECA LIMITED (GB) | 1996-10-08 | — | — | US | disclosed |
| EP-0690847-A1 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1996-01-10 | — | — | EP | disclosed |
| WO-1994022835-A2 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1994-10-13 | — | — | WO | disclosed |