Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.41 |
| ▸ | THRA | P10827 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | KHK | P50053 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8635323 | 0.87 | CNR1 (0.49) | CNR1CNR2ALDH1A1MAPTPLA2G2A | |
| SCHEMBL7401051 | 0.84 | DRD4 (0.42) | THRBMAPTPLA2G2AKHK | |
| Trifluoroacetic Acid SCHEMBL8698735 | 0.78 | SERPINE1 (0.41) | CNR2THRBMAPT | |
| SCHEMBL7396359 | 0.73 | CNR1 (0.52) | CNR1CNR2ALDH1A1PLA2G2A | |
| SCHEMBL7402500 | 0.72 | METAP1 (0.51) | METAP1ITGB3ITGA2BMAPTHRH3 | |
| SCHEMBL7440853 | 0.71 | CNR1 (0.52) | CNR1CNR2ALDH1A1PLA2G2A | |
| SCHEMBL7392232 | 0.66 | HRH3 (0.54) | ITGB3ITGA2BMAPTF10HRH3 | |
| SCHEMBL7402423 | 0.66 | USP2 (0.54) | ITGB3ITGA2BTHRBALDH1A1MAPT | |
| SCHEMBL7403661 | 0.66 | MCHR1 (0.48) | METAP1ITGB3ITGA2BKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL7402791 | 0.65 | THRB (0.58) | ITGB3ITGA2BTHRBHRH3HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563141-A | INHIBIT CELL ADHESION FOR EXAMPLE, PLATELET AGGRE GATION | ZENECA LIMITED (GB) | 1996-10-08 | — | — | US | disclosed |
| EP-0690847-A1 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1996-01-10 | — | — | EP | disclosed |
| WO-1994022835-A2 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1994-10-13 | — | — | WO | disclosed |