Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 1/20 | 0.51 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.47 |
| ▸ | NCF1 | P14598 | 1/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | CDK8 | P49336 | 3/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | CCNC | P24863 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7399086 | 0.88 | SLC22A12 (0.49) | METAP1ITGB3ITGA2BNCF1PDGFRB | |
| SCHEMBL7403661 | 0.78 | MCHR1 (0.48) | METAP1ITGB3ITGA2BMEN1KMT2A | |
| SCHEMBL7399584 | 0.72 | GAA (0.47) | ITGB3ITGA2BGAAMEN1KMT2A | |
| SCHEMBL7399588 | 0.72 | METAP1 (0.45) | METAP1ITGB3ITGA2BMAPTHRH3 | |
| SCHEMBL7327928 | 0.71 | HRH3 (0.59) | ITGB3ITGA2BMEN1KMT2AHRH3 | |
| SCHEMBL7402423 | 0.71 | USP2 (0.54) | ITGB3ITGA2BGAAMEN1KMT2A | |
| SCHEMBL7403828 | 0.71 | MEN1 (0.49) | ITGB3ITGA2BGAAMEN1KMT2A | |
| SCHEMBL7398480 | 0.71 | ITGB3 (0.53) | ITGB3ITGA2BKCNH2HRH3 | |
| SCHEMBL7399643 | 0.71 | HRH1 (0.57) | ITGB3ITGA2BKCNH2HRH3 | |
| SCHEMBL9080607 | 0.70 | ITGB3 (0.49) | ITGB3ITGA2BMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563141-A | INHIBIT CELL ADHESION FOR EXAMPLE, PLATELET AGGRE GATION | ZENECA LIMITED (GB) | 1996-10-08 | — | — | US | disclosed |
| EP-0690847-A1 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1996-01-10 | — | — | EP | disclosed |
| WO-1994022835-A2 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1994-10-13 | — | — | WO | disclosed |