Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.35 |
| ▸ | ACE | P12821 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | CASP1 | P29466 | 2/20 | 0.31 |
| ▸ | CASP3 | P42574 | 2/20 | 0.31 |
| ▸ | CASP7 | P55210 | 2/20 | 0.31 |
| ▸ | CASP6 | P55212 | 2/20 | 0.31 |
| ▸ | CASP8 | Q14790 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | GBA1 | P04062 | 1/20 | 0.30 |
| ▸ | G6PD | P11413 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7394661 | 0.85 | EPHX2 (0.36) | ALDH1A1LMNAEPHX2ACEKMT2A | |
| Amantadine SCHEMBL7400188 | 0.83 | ACE (0.36) | ALDH1A1LMNAEPHX2ACEKMT2A | |
| Amantadine SCHEMBL7400190 | 0.83 | ACE (0.36) | ALDH1A1LMNAEPHX2ACEKMT2A | |
| SCHEMBL7396702 | 0.81 | ALDH1A1 (0.38) | ALDH1A1LMNAKMT2A | |
| SCHEMBL7398631 | 0.81 | ACE (0.45) | ALDH1A1EPHX2ACEKMT2AMEN1 | |
| SCHEMBL7389645 | 0.80 | ALDH1A1 (0.35) | ALDH1A1EPHX2KMT2AMEN1MAPT | |
| SCHEMBL7396582 | 0.80 | ALDH1A1 (0.36) | ALDH1A1LMNAEPHX2KMT2AMEN1 | |
| SCHEMBL7399896 | 0.79 | LMNA (0.39) | ALDH1A1LMNAACEKMT2AHPGD | |
| SCHEMBL7399898 | 0.79 | LMNA (0.39) | ALDH1A1LMNAACEKMT2AHPGD | |
| SCHEMBL7399507 | 0.79 | HSD11B1 (0.35) | ALDH1A1LMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0535042-B1 | ANGIOTENSIS CONVERTING ENZYME INHIBITORS | FISONS PLC (GB) | 1995-03-29 | — | — | EP | disclosed |
| US-5348978-A | Angiotensin converting enzyme inhibitors | FISONS PLC (GB) | 1994-09-20 | — | — | US | disclosed |
| EP-0535042-A1 | ANGIOTENSIS CONVERTING ENZYME INHIBITORS. | FISONS PLC (GB) | 1993-04-07 | — | — | EP | disclosed |
| WO-1992000276-A2 | ANGIOTENSIS CONVERTING ENZYME INHIBITORS | FISONS PLC (GB) | 1992-01-09 | — | — | WO | disclosed |