Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSIP1 | O75475 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 9/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7370842 | 0.78 | PSIP1 (0.48) | PSIP1HSD11B1MAPTCYP1A2GAA | |
| SCHEMBL20350438 | 0.76 | PSIP1 (0.50) | PSIP1HSD11B1MAPTCYP1A2GAA | |
| SCHEMBL8150284 | 0.75 | PSIP1 (0.54) | PSIP1HSD11B1MAPTCYP1A2GAA | |
| SCHEMBL24062675 | 0.74 | PSIP1 (0.44) | PSIP1HSD11B1MAPTCYP1A2GAA | |
| SCHEMBL13948507 | 0.73 | HSD11B1 (0.46) | PSIP1HSD11B1MAPTCYP1A2GAA | |
| SCHEMBL4780746 | 0.73 | SRR (0.61) | CYP1A2 | |
| Hydrochloric Acid SCHEMBL5754335 | 0.73 | SRR (0.61) | CYP1A2 | |
| SCHEMBL8414713 | 0.72 | POLB (0.47) | PSIP1HSD11B1MMP13MEN1KMT2A | |
| SCHEMBL9218545 | 0.72 | POLB (0.47) | PSIP1HSD11B1MMP13MEN1KMT2A | |
| SCHEMBL7369644 | 0.71 | CYP1A2 (0.50) | CYP1A2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0929519-A1 | $g(b)-SULFONYL HYDROXAMIC ACIDS AS MATRIX METALLOPROTEINASES INHIBITORS | PHARMACIA & UPJOHN COMPANY (US) | 1999-07-21 | — | — | EP | claimed |
| WO-1998013340-A1 | β-SULFONYL HYDROXAMIC ACIDS AS MATRIX METALLOPROTEINASES INHIBITORS | PHARMACIA & UPJOHN COMPANY (US) | 1998-04-02 | — | — | WO | claimed |
| EP-0929519-A1 | $g(b)-SULFONYL HYDROXAMIC ACIDS AS MATRIX METALLOPROTEINASES INHIBITORS | PHARMACIA & UPJOHN COMPANY (US) | 1999-07-21 | — | — | EP | disclosed |
| WO-1998013340-A1 | β-SULFONYL HYDROXAMIC ACIDS AS MATRIX METALLOPROTEINASES INHIBITORS | PHARMACIA & UPJOHN COMPANY (US) | 1998-04-02 | — | — | WO | disclosed |