Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MMP13 | P45452 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ESRRB | O95718 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9218545 | 1.00 | POLB (0.47) | POLBPSIP1HSD11B1KMT2AMMP13 | |
| SCHEMBL29128604 | 0.85 | KMT2A (0.50) | POLBKMT2AMMP13ESRRB | |
| SCHEMBL28253203 | 0.85 | ALDH1A1 (0.47) | KMT2AMMP13MEN1 | |
| SCHEMBL7365625 | 0.82 | PSIP1 (0.52) | POLBPSIP1HSD11B1KMT2AMEN1 | |
| SCHEMBL7370842 | 0.79 | PSIP1 (0.48) | POLBPSIP1HSD11B1KMT2AMMP13 | |
| SCHEMBL6550974 | 0.78 | HSD11B1 (0.49) | PSIP1HSD11B1KMT2AMEN1 | |
| SCHEMBL9626716 | 0.76 | HSD11B1 (0.62) | POLBHSD11B1KMT2AMMP13MEN1 | |
| SCHEMBL7141503 | 0.76 | PSIP1 (0.48) | POLBPSIP1HSD11B1KMT2AMMP13 | |
| SCHEMBL7135389 | 0.76 | PSIP1 (0.48) | POLBPSIP1HSD11B1KMT2AMMP13 | |
| SCHEMBL23489134 | 0.75 | PSIP1 (0.44) | PSIP1HSD11B1KMT2AMMP13MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0932598-A1 | ASPARTATE ESTER INHIBITORS OF INTERLEUKIN-1$g(b) CONVERTING ENZYME | WARNER-LAMBERT COMPANY (US) | 1999-08-04 | — | — | EP | disclosed |
| WO-1998016502-A1 | ASPARTATE ESTER INHIBITORS OF INTERLEUKIN-1β CONVERTING ENZYME | WARNER-LAMBERT COMPANY (US) | 1998-04-23 | — | — | WO | disclosed |