SCHEMBL740037

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14330972	0.85	TAS1R3 (0.48)	EPHX2NR1H4NAMPTALDH1A1ACACB
	SCHEMBL2458608	0.82	KMT2A (0.50)	NAMPTACACBMAPK14ULK1MLYCD
	SCHEMBL737425	0.82	KMT2A (0.50)	NAMPTACACBMAPK14ULK1MLYCD
	SCHEMBL2660613	0.82	EPHX2 (0.50)	EPHX2NR1H4ALDH1A1MLYCDSMN1; SMN2
	SCHEMBL23116863	0.80	GFER (0.53)	NAMPTALDH1A1ACACBMAPK14ULK1
	SCHEMBL4187911	0.80	CES2 (0.55)	EPHX2MAPK14MLYCD
	SCHEMBL12188582	0.80	EPHX2 (0.50)	EPHX2NR1H4NAMPTALDH1A1ACACB
	SCHEMBL12641858	0.80	GAA (0.57)	EPHX2NR1H4ALDH1A1LMNAHPGD
	SCHEMBL15427269	0.79	TRPV1 (0.51)	NAMPTACACBMAPK14ULK1MLYCD
	SCHEMBL21198695	0.79	OGG1 (0.55)	ALDH1A1ACACBSMN1; SMN2NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.