Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LNPEP | Q9UIQ6 | 5/20 | 0.59 |
| ▸ | ANPEP | P15144 | 4/20 | 0.59 |
| ▸ | ACE | P12821 | 10/20 | 0.54 |
| ▸ | MME | P08473 | 6/20 | 0.53 |
| ▸ | CPA1 | P15085 | 5/20 | 0.53 |
| ▸ | ACE2 | Q9BYF1 | 5/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7401025 | 1.00 | LNPEP (0.59) | LNPEPANPEPACEMMECPA1 | |
| SCHEMBL7405758 | 1.00 | LNPEP (0.59) | LNPEPANPEPACEMMECPA1 | |
| SCHEMBL7548954 | 1.00 | LNPEP (0.59) | LNPEPANPEPACEMMECPA1 | |
| SCHEMBL7500763 | 1.00 | LNPEP (0.59) | LNPEPANPEPACEMMECPA1 | |
| SCHEMBL7403012 | 0.97 | LNPEP (0.62) | LNPEPANPEPACEMMECPA1 | |
| SCHEMBL7365722 | 0.89 | LNPEP (0.49) | LNPEPANPEPACEMMECPA1 | |
| SCHEMBL7365573 | 0.88 | PTPN1 (0.59) | ACEMMEPTPN1CA1CA2 | |
| SCHEMBL11314288 | 0.82 | ACE (0.64) | ACEMMECPA1ACE2 | |
| Alcohol SCHEMBL19231109 | 0.76 | CTSL (0.65) | ACEMMECPA1ACE2PTPN1 | |
| SCHEMBL7369936 | 0.76 | PTPN1 (0.51) | ACEMMEPTPN1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0920307-A2 | DERIVATES FROM BISARYLTETRACARBONACID, AND PHARMARCEUTICAL PRODUCT CONTAINING THEM | Roche Diagnostics GmbH (DE) | 1999-06-09 | — | — | EP | disclosed |
| WO-1998006386-A2 | DERIVATES FROM BISARYLTETRACARBONACID, AND PHARMARCEUTICAL PRODUCT CONTAINING THEM | ROCHE DIAGNOSTICS GMBH (DE) | 1998-02-19 | — | — | WO | disclosed |