Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.51 |
| ▸ | ACE | P12821 | 5/20 | 0.45 |
| ▸ | CA1 | P00915 | 3/20 | 0.45 |
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.44 |
| ▸ | MME | P08473 | 1/20 | 0.44 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.43 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.43 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7368170 | 0.95 | PTPN1 (0.53) | PTPN1ACECA1CA2CA12 | |
| SCHEMBL7365722 | 0.91 | LNPEP (0.49) | PTPN1ACECA1CA2CA12 | |
| SCHEMBL7365573 | 0.86 | PTPN1 (0.59) | PTPN1ACECA1CA2GPR132 | |
| SCHEMBL7370637 | 0.77 | AGTR2 (0.48) | CA1CA2AGTR2 | |
| SCHEMBL7400488 | 0.76 | LNPEP (0.59) | PTPN1ACECA1CA2CA12 | |
| SCHEMBL7405758 | 0.76 | LNPEP (0.59) | PTPN1ACECA1CA2CA12 | |
| SCHEMBL7548954 | 0.76 | LNPEP (0.59) | PTPN1ACECA1CA2CA12 | |
| SCHEMBL7500763 | 0.76 | LNPEP (0.59) | PTPN1ACECA1CA2CA12 | |
| SCHEMBL7401025 | 0.76 | LNPEP (0.59) | PTPN1ACECA1CA2CA12 | |
| SCHEMBL5793343 | 0.74 | CA2 (0.69) | PTPN1ACECA1CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0920307-A2 | DERIVATES FROM BISARYLTETRACARBONACID, AND PHARMARCEUTICAL PRODUCT CONTAINING THEM | Roche Diagnostics GmbH (DE) | 1999-06-09 | — | — | EP | disclosed |
| WO-1998006386-A2 | DERIVATES FROM BISARYLTETRACARBONACID, AND PHARMARCEUTICAL PRODUCT CONTAINING THEM | ROCHE DIAGNOSTICS GMBH (DE) | 1998-02-19 | — | — | WO | disclosed |