Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LNPEP | Q9UIQ6 | 5/20 | 0.49 |
| ▸ | ANPEP | P15144 | 4/20 | 0.49 |
| ▸ | ACE | P12821 | 8/20 | 0.46 |
| ▸ | MME | P08473 | 3/20 | 0.43 |
| ▸ | CPA1 | P15085 | 2/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.40 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7369936 | 0.91 | PTPN1 (0.51) | ACEMMEPTPN1CA12CA1 | |
| SCHEMBL7370637 | 0.90 | AGTR2 (0.48) | LNPEPANPEPCA1CA2AGTR2 | |
| SCHEMBL7500763 | 0.89 | LNPEP (0.59) | LNPEPANPEPACEMMECPA1 | |
| SCHEMBL7400488 | 0.89 | LNPEP (0.59) | LNPEPANPEPACEMMECPA1 | |
| SCHEMBL7548954 | 0.89 | LNPEP (0.59) | LNPEPANPEPACEMMECPA1 | |
| SCHEMBL7401025 | 0.89 | LNPEP (0.59) | LNPEPANPEPACEMMECPA1 | |
| SCHEMBL7405758 | 0.89 | LNPEP (0.59) | LNPEPANPEPACEMMECPA1 | |
| SCHEMBL7368170 | 0.86 | PTPN1 (0.53) | ACEPTPN1CA12CA1CA9 | |
| SCHEMBL7403012 | 0.86 | LNPEP (0.62) | LNPEPANPEPACEMMECPA1 | |
| SCHEMBL7444103 | 0.85 | AGTR2 (0.44) | LNPEPANPEPCA1CA2AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0920307-A2 | DERIVATES FROM BISARYLTETRACARBONACID, AND PHARMARCEUTICAL PRODUCT CONTAINING THEM | Roche Diagnostics GmbH (DE) | 1999-06-09 | — | — | EP | disclosed |
| WO-1998006386-A2 | DERIVATES FROM BISARYLTETRACARBONACID, AND PHARMARCEUTICAL PRODUCT CONTAINING THEM | ROCHE DIAGNOSTICS GMBH (DE) | 1998-02-19 | — | — | WO | disclosed |