Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.71 |
| ▸ | MEN1 | O00255 | 2/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.57 |
| ▸ | GSK3B | P49841 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.53 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7396831 | 0.86 | LMNA (0.63) | ALDH1A1MEN1KMT2ALMNATP53 | |
| SCHEMBL7394036 | 0.85 | ALDH1A1 (0.77) | ALDH1A1MEN1KMT2ALMNATP53 | |
| SCHEMBL9660574 | 0.85 | ALDH1A1 (0.68) | ALDH1A1MEN1KMT2ALMNATP53 | |
| SCHEMBL17974011 | 0.84 | ALDH1A1 (1.00) | ALDH1A1MEN1KMT2ALMNATP53 | |
| SCHEMBL9718385 | 0.83 | ALDH1A1 (0.64) | ALDH1A1MEN1KMT2ALMNATP53 | |
| SCHEMBL10463166 | 0.81 | ALDH1A1 (0.61) | ALDH1A1MEN1KMT2ALMNATP53 | |
| SCHEMBL29019309 | 0.80 | ALDH1A1 (0.84) | ALDH1A1MEN1KMT2ALMNAAKR1C3 | |
| SCHEMBL5925404 | 0.80 | ALDH1A1 (0.84) | ALDH1A1MEN1KMT2ALMNATP53 | |
| SCHEMBL11104856 | 0.80 | ALDH1A1 (0.77) | ALDH1A1MEN1KMT2ALMNATP53 | |
| SCHEMBL7406463 | 0.78 | HDAC3 (0.69) | ALDH1A1MEN1KMT2ALMNAGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563141-A | INHIBIT CELL ADHESION FOR EXAMPLE, PLATELET AGGRE GATION | ZENECA LIMITED (GB) | 1996-10-08 | — | — | US | disclosed |
| EP-0690847-A1 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1996-01-10 | — | — | EP | disclosed |
| WO-1994022835-A2 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1994-10-13 | — | — | WO | disclosed |