Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.43 |
| ▸ | MIF | P14174 | 1/20 | 0.42 |
| ▸ | ITGAV | P06756 | 2/20 | 0.40 |
| ▸ | KDM1A | O60341 | 6/20 | 0.38 |
| ▸ | RCOR1 | Q9UKL0 | 6/20 | 0.38 |
| ▸ | MAOA | P21397 | 5/20 | 0.37 |
| ▸ | KDM1B | Q8NB78 | 5/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7400582 | 1.00 | ITGB3 (0.43) | ITGB3ITGA2BMIFITGAVKDM1A | |
| SCHEMBL7400576 | 0.86 | ITGB3 (0.43) | ITGB3ITGA2BITGAVKMT2AMAPT | |
| SCHEMBL7400574 | 0.84 | ITGB3 (0.46) | ITGB3ITGA2BITGAVKDM1ARCOR1 | |
| SCHEMBL7433070 | 0.81 | ITGB3 (0.68) | ITGB3ITGA2BMIFITGAV | |
| SCHEMBL7396918 | 0.78 | ITGB3 (0.68) | ITGB3ITGA2BMIFITGAV | |
| SCHEMBL7401123 | 0.74 | MIF (0.46) | ITGB3ITGA2BMIFKDM1ARCOR1 | |
| SCHEMBL6675234 | 0.72 | ITGB3 (0.48) | ITGB3ITGA2BMIFITGAV | |
| SCHEMBL7401125 | 0.71 | ITGB3 (0.51) | ITGB3ITGA2BMIFCA1CA2 | |
| SCHEMBL7401638 | 0.71 | ITGB3 (0.50) | ITGB3ITGA2BMIFITGAVKDM1A | |
| SCHEMBL7402544 | 0.71 | ITGB3 (0.46) | ITGB3ITGA2BITGAVKDM1ARCOR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0593603-B1 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2002-11-20 | — | — | EP | disclosed |
| US-6127359-A | Bicyclic fibrinogen antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 2000-10-03 | — | — | US | disclosed |
| EP-0593603-A1 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1994-04-27 | — | — | EP | disclosed |
| WO-1993000095-A2 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-01-07 | — | — | WO | disclosed |