Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 13/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 13/20 | 0.43 |
| ▸ | ITGAV | P06756 | 2/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7400582 | 0.86 | ITGB3 (0.43) | ITGB3ITGA2BITGAVMAPTKMT2A | |
| SCHEMBL7400579 | 0.86 | ITGB3 (0.43) | ITGB3ITGA2BITGAVMAPTKMT2A | |
| SCHEMBL7400574 | 0.81 | ITGB3 (0.46) | ITGB3ITGA2BITGAVOPRM1OPRD1 | |
| SCHEMBL7404826 | 0.71 | ITGB3 (0.52) | ITGB3ITGA2BITGAVHDAC1HDAC8 | |
| SCHEMBL7401590 | 0.70 | ITGB3 (0.56) | ITGB3ITGA2BITGAV | |
| SCHEMBL7396292 | 0.69 | ALDH1A1 (0.39) | ITGB3ITGA2BITGAVSMN1; SMN2ALDH1A1 | |
| SCHEMBL7396300 | 0.69 | ALDH1A1 (0.39) | ITGB3ITGA2BITGAVSMN1; SMN2ALDH1A1 | |
| SCHEMBL7396296 | 0.69 | ALDH1A1 (0.39) | ITGB3ITGA2BITGAVSMN1; SMN2ALDH1A1 | |
| SCHEMBL7402544 | 0.69 | ITGB3 (0.46) | ITGB3ITGA2BITGAVHDAC1HDAC8 | |
| SCHEMBL7393661 | 0.68 | ITGB3 (0.53) | ITGB3ITGA2BITGAVHDAC1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0593603-B1 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2002-11-20 | — | — | EP | disclosed |
| US-6127359-A | Bicyclic fibrinogen antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 2000-10-03 | — | — | US | disclosed |
| EP-0593603-A1 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1994-04-27 | — | — | EP | disclosed |
| WO-1993000095-A2 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-01-07 | — | — | WO | disclosed |