Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 10/20 | 0.61 |
| ▸ | MMP13 | P45452 | 3/20 | 0.61 |
| ▸ | MMP9 | P14780 | 3/20 | 0.61 |
| ▸ | MMP2 | P08253 | 10/20 | 0.56 |
| ▸ | MMP3 | P08254 | 9/20 | 0.56 |
| ▸ | PDE4A | P27815 | 8/20 | 0.56 |
| ▸ | PDE4B | Q07343 | 8/20 | 0.56 |
| ▸ | PDE4C | Q08493 | 8/20 | 0.56 |
| ▸ | PDE4D | Q08499 | 8/20 | 0.56 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6933282 | 0.78 | MMP1 (0.76) | MMP1MMP13MMP9MMP2MMP3 | |
| SCHEMBL7363783 | 0.76 | MMP1 (0.53) | MMP1MMP13MMP9MMP2MMP3 | |
| SCHEMBL6931491 | 0.76 | MMP1 (1.00) | MMP1MMP13MMP9MMP2MMP3 | |
| SCHEMBL7073256 | 0.75 | MMP2 (0.77) | MMP1MMP13MMP9MMP2MMP3 | |
| SCHEMBL8843348 | 0.74 | MMP1 (0.51) | MMP1MMP13MMP9MMP2MMP3 | |
| SCHEMBL28285284 | 0.74 | LDHA (0.60) | PPARGPPARAALDH1A1 | |
| SCHEMBL6934585 | 0.73 | MMP1 (0.70) | MMP1MMP13MMP9MMP2MMP3 | |
| SCHEMBL7207040 | 0.73 | MMP1 (0.76) | MMP1MMP13MMP9MMP2MMP3 | |
| SCHEMBL6824624 | 0.72 | MMP2 (1.00) | MMP1MMP13MMP9MMP2MMP3 | |
| SCHEMBL4796914 | 0.72 | NPC1 (0.58) | MMP1MMP13MMP9MMP2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0871439-A4 | SUBSTITUTED (ARYL, HETEROARYL, ARYLMETHYL OR HETEROARYLMETHYL) HYDROXAMIC ACID COMPOUNDS | RHONE POULENC RORER PHARMA (US) | 1999-07-21 | — | — | EP | disclosed |
| EP-0871439-A1 | SUBSTITUTED (ARYL, HETEROARYL, ARYLMETHYL OR HETEROARYLMETHYL) HYDROXAMIC ACID COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS, INC. (US) | 1998-10-21 | — | — | EP | disclosed |
| WO-1997024117-A1 | SUBSTITUTED (ARYL, HETEROARYL, ARYLMETHYL OR HETEROARYLMETHYL) HYDROXAMIC ACID COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1997-07-10 | — | — | WO | disclosed |